ACITROM 4 MG TAB

About

ACITROM 4 MG TAB contains acenocoumarol, an oral anticoagulant that functions as a vitamin K antagonist. This medication works by interfering with the liver's ability to produce several clotting factors (specifically factors II, VII, IX, and X) that depend on vitamin K for their activation. By reducing the levels of these active clotting factors, acenocoumarol effectively thins the blood, thereby decreasing its propensity to form harmful clots. It is widely used in the prevention and treatment of various thromboembolic conditions, such as deep vein thrombosis, pulmonary embolism, and to prevent stroke in patients with atrial fibrillation. Due to its potent effect on blood clotting, careful and regular monitoring of the International Normalized Ratio (INR) is essential to ensure therapeutic efficacy and minimize the risk of bleeding complications.

Uses

• Prevention and treatment of deep vein thrombosis (DVT)
• Management of pulmonary embolism (PE)
• Prevention of systemic embolism in atrial fibrillation
• Prophylaxis of thromboembolic complications post-surgery

Directions For Use

Take exactly as prescribed by your doctor, usually once daily at the same time. Regular INR monitoring is essential.

Benefits

• Effectively prevents blood clot formation
• Reduces the risk of stroke in high-risk patients
• Treats existing deep vein thrombosis and pulmonary embolism
• Prevents recurrent thromboembolic events
• Manages blood clotting in atrial fibrillation
• Improves cardiovascular outcomes in specific conditions

Side Effects

• Bleeding (e.g., nosebleeds, gum bleeding, bruising)
• Nausea
• Vomiting
• Diarrhea
• Abdominal pain
• Skin rash
• Hair loss
• Elevated liver enzymes
• Headache
• Dizziness
• Fatigue
• Purple toe syndrome (rare)

Safety Measures

• Alcohol - Avoid or limit alcohol intake as it can significantly affect INR levels and increase the risk of bleeding.
• Pregnancy - Contraindicated during pregnancy due0 to teratogenic effects and risk of fetal hemorrhage; use effective contraception.
• Breastfeeding - Generally not recommended during breastfeeding; consult your doctor as alternatives may be safer.
• Liver - Contraindicated in severe liver disease due to impaired clotting factor synthesis and increased bleeding risk.
• Kidney - Use with caution in severe renal impairment; dose adjustment may be necessary with close INR monitoring.
• Lung - No specific contraindications related to lung conditions, but use with caution in patients with active pulmonary hemorrhage.

Disclaimer

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