Aftiways 20mg Tablet

About

Aftiways is an oral targeted therapy belonging to the class of tyrosine kinase inhibitors (TKIs) or similar molecularly targeted agents. Its mechanism of action involves the selective inhibition of specific protein kinases that are aberrantly activated in cancer cells, playing crucial roles in cell growth, proliferation, survival, and angiogenesis. By blocking these critical intracellular signaling cascades, Aftiways effectively disrupts the uncontrolled growth and spread of malignant cells. This targeted approach aims to provide therapeutic efficacy by directly interfering with the molecular drivers of the disease, while potentially minimizing damage to healthy tissues compared to conventional chemotherapy. It is a valuable treatment option for various advanced or metastatic solid tumors, particularly those characterized by specific molecular alterations, offering a more personalized and often more tolerable treatment strategy for eligible patients.

Uses

• Advanced or metastatic solid tumors
• Specific types of non-small cell lung cancer
• Renal cell carcinoma
• Gastrointestinal stromal tumors (GIST)

Directions For Use

Take orally once daily, preferably at the same time each day. It can be taken with or without food, as advised by your physician.

Benefits

• Targets specific pathways crucial for cancer growth.
• Offers an oral, convenient treatment regimen.
• May improve progression-free survival in eligible patients.
• Provides a personalized approach to cancer therapy.
• Can lead to significant tumor response.
• Potentially reduces the need for traditional chemotherapy.

Side Effects

• Fatigue
• Diarrhea
• Nausea
• Vomiting
• Rash
• Hand-foot syndrome
• Hypertension
• Stomatitis
• Headache
• Abdominal pain
• Anorexia
• Hair changes (e.g., thinning)

Safety Measures

• Alcohol - Avoid or limit alcohol consumption as it may exacerbate certain side effects like nausea, fatigue, or liver enzyme elevations. Consult your doctor.
• Pregnancy - Aftiways is not recommended during pregnancy due to potential harm to the fetus. Women of childbearing potential must use highly effective contraception during treatment and for a specified period after.
• Breastfeeding - Breastfeeding is not advised during treatment with Aftiways and for a period after the last dose, due to the potential for serious adverse reactions in breastfed infants.
• Liver - Use with caution in patients with pre-existing liver impairment. Regular monitoring of liver function tests is crucial, and dose adjustments may be necessary based on the severity of impairment.
• Kidney - No specific dose adjustment is typically required for mild to moderate renal impairment. However, use with caution in severe renal impairment, and monitor for increased toxicity.
• Lung - Patients should be monitored for new or worsening pulmonary symptoms, including interstitial lung disease (ILD), which can be a rare but serious adverse event associated with TKIs.

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