ALFUGRESS-D 10

About

This medication combines Alfuzosin, an alpha-1 adrenergic receptor antagonist, with Dutasteride, a dual 5-alpha reductase inhibitor, to provide comprehensive treatment for benign prostatic hyperplasia (BPH). Alfuzosin works by relaxing the smooth muscles in the prostate, bladder neck, and urethra, which helps to improve urine flow and rapidly alleviate lower urinary tract symptoms (LUTS) such as urinary hesitancy, weak stream, and incomplete bladder emptying. Dutasteride, on the other hand, acts by inhibiting both type 1 and type 2 5-alpha reductase enzymes, thereby preventing the conversion of testosterone to dihydrotestosterone (DHT), a key hormone responsible for prostate growth. This leads to a significant reduction in prostate volume over time, addressing the underlying cause of BPH progression. The combination therapy offers both rapid symptomatic relief and long-term benefits, including a reduced risk of acute urinary retention and the need for BPH-related surgery, making it an effective option for men with moderate to severe BPH and an enlarged prostate.

Uses

• Treatment of moderate to severe symptoms of benign prostatic hyperplasia (BPH).
• Reduction of the risk of BPH progression.
• Improvement of urinary flow and bladder emptying.
• Prevention of acute urinary retention and need for BPH-related surgery.

Directions For Use

Take orally, usually once daily immediately after the same meal each day. Swallow the tablet whole; do not crush or chew.

Benefits

• Provides rapid and sustained relief of BPH symptoms.
• Reduces prostate volume over time.
• Improves urinary flow and bladder emptying.
• Decreases the risk of BPH-related complications.
• Offers comprehensive dual-action BPH management.
• Enhances quality of life for BPH patients.

Side Effects

• Dizziness
• Orthostatic hypotension
• Headache
• Fatigue
• Nausea
• Abdominal pain
• Decreased libido
• Erectile dysfunction
• Breast tenderness or enlargement
• Retrograde ejaculation (less common)
• Allergic reactions (rare)
• Depressed mood

Safety Measures

• Alcohol - Alcohol may increase the risk of dizziness and orthostatic hypotension when taken with this medication. Limit or avoid alcohol consumption.
• Pregnancy - Contraindicated in women, especially pregnant women or those who may become pregnant, due to the risk of fetal abnormalities.
• Breastfeeding - Contraindicated in women. Dutasteride may be absorbed through the skin, posing a risk to infants.
• Liver - Use with caution in mild to moderate hepatic impairment; contraindicated in severe hepatic impairment.
• Kidney - Use with caution in patients with severe renal impairment.
• Lung - Generally safe for use in patients with lung conditions, but caution is advised in those with severe asthma due to potential for bronchospasm, though rare.

Disclaimer

MedEHub is committed to delivering reliable, expert-reviewd information to help consumers make informed health decisions. However, the content provided on this website is for informational purposes only and is not intended to replace professional medical advice, diagnosis or treatment.

Always consult your doctor for any medical concerns, and discuss your questions about health conditions or medications with a qualified healthcare professional. Do not ignore or delay seeking professional medical advice based on information found on Med E Hub.

Our goal is to complement, not replace, the essential doctor-patient relationship.