ANGLOFF-OZ TAB 10 S

About

Angloff-OZ Tablet is a powerful fixed-dose combination antimicrobial medication, typically comprising Ofloxacin and Ornidazole, designed to combat a broad spectrum of infections. Ofloxacin, a potent fluoroquinolone antibiotic, exerts its bactericidal action by inhibiting bacterial DNA gyrase and topoisomerase IV, crucial enzymes required for bacterial DNA replication, transcription, repair, and recombination, ultimately leading to bacterial cell death. Ornidazole, a nitroimidazole derivative, functions as both an antibiotic and an antiprotozoal agent. It penetrates microbial cells and damages their DNA, effectively eradicating susceptible anaerobic bacteria and various protozoa. This synergistic combination provides comprehensive coverage against a wide array of bacterial and protozoal pathogens, rendering it highly effective in the treatment of mixed infections, particularly those impacting the gastrointestinal tract, genitourinary system, and various soft tissue infections, ensuring a more complete therapeutic response.

Uses

• Treatment of bacterial and protozoal infections
• Management of gastrointestinal infections
• Therapy for genitourinary tract infections
• Treatment of mixed infections

Directions For Use

Take one tablet twice daily, preferably after meals, or as prescribed by your doctor. Complete the full course of medication.

Benefits

• Broad-spectrum antimicrobial action
• Effective against bacterial and protozoal pathogens
• Treats mixed infections
• Reduces infection symptoms
• Prevents recurrence of certain infections
• Convenient oral administration

Side Effects

• Nausea
• Vomiting
• Diarrhea
• Abdominal pain
• Headache
• Dizziness
• Metallic taste
• Insomnia
• Rash
• Photosensitivity
• Tendonitis/Tendon rupture (rare)
• Peripheral neuropathy (rare)

Safety Measures

• Alcohol - Avoid alcohol during treatment and for at least 48 hours after the last dose due to potential disulfiram-like reactions with Ornidazole.
• Pregnancy - Not recommended during pregnancy, especially in the first trimester. Consult a doctor for risks vs. benefits.
• Breastfeeding - Not recommended during breastfeeding as both components pass into breast milk.
• Liver - Use with caution and dose adjustment in patients with severe liver impairment.
• Kidney - Use with caution and dose adjustment in patients with kidney impairment.
• Lung - Use with caution in patients with a history of seizures or conditions affecting the central nervous system, which could impact respiratory control.

Disclaimer

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