APRINEON 125 MG CAP. 1X3 CAP.

About

APRINEON 125 MG CAP. is an antiemetic medication specifically formulated to prevent chemotherapy-induced nausea and vomiting (CINV). It belongs to a class of drugs known as neurokinin-1 (NK1) receptor antagonists, which work by blocking the action of substance P, a neurotransmitter involved in the emetic reflex. By targeting this specific pathway, APRINEON effectively reduces both acute and delayed phases of CINV, significantly improving patient comfort and adherence to their chemotherapy regimens. The medication is typically administered orally as part of a multi-day regimen, often in combination with other antiemetics like corticosteroids and serotonin (5-HT3) receptor antagonists, to provide comprehensive protection against emesis.

The short course of APRINEON capsules is designed for convenient dosing around chemotherapy administration, ensuring optimal prophylactic coverage. Its efficacy in preventing severe nausea and vomiting allows patients to maintain better nutritional status and overall quality of life during their cancer treatment. Healthcare providers carefully consider the emetogenicity of the chemotherapy regimen when prescribing APRINEON, tailoring its use to maximize benefits. Patients are advised on the importance of taking the medication exactly as prescribed to achieve the best possible antiemetic control and minimize the distressing symptoms associated with chemotherapy.

Uses

• Prevention of acute chemotherapy-induced nausea and vomiting (CINV)
• Prevention of delayed CINV
• Adjunct therapy with other antiemetics
• Management of highly emetogenic chemotherapy regimens

Directions For Use

Take orally, usually before chemotherapy, as directed by your physician. Swallow the capsule whole with water.

Benefits

• Significantly reduces chemotherapy-induced nausea
• Provides effective control of vomiting
• Improves patient comfort during chemotherapy
• Enhances adherence to cancer treatment
• Effective for both acute and delayed CINV
• Convenient oral dosing regimen

Side Effects

• Fatigue and asthenia
• Headache
• Dizziness
• Constipation or diarrhea
• Hiccups
• Dyspepsia (indigestion)
• Anorexia (loss of appetite)
• Elevated liver enzymes
• Neutropenia (low white blood cell count)
• Rash
• Abdominal pain
• Mild allergic reactions

Safety Measures

• Alcohol - Generally safe, but excessive alcohol consumption may exacerbate gastrointestinal upset or contribute to fatigue.
• Pregnancy - Consult a doctor before use during pregnancy; use only if the potential benefit justifies the potential risk to the fetus.
• Breastfeeding - Not recommended during breastfeeding as it is unknown if the drug is excreted in breast milk.
• Liver - Use with caution in patients with severe liver impairment; dose adjustment may be necessary, and liver function should be monitored.
• Kidney - No dose adjustment is typically needed for patients with mild to moderate kidney impairment.
• Lung - Generally safe for patients with lung conditions; no specific lung-related precautions are usually required.

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