ARIRAZO 5 TAB

About

This medication contains Aripiprazole, an atypical antipsychotic widely used for the treatment of schizophrenia, acute manic and mixed episodes associated with bipolar I disorder, and as an adjunctive therapy for major depressive disorder. Its unique pharmacological profile involves acting as a partial agonist at dopamine D2 and serotonin 5-HT1A receptors, and an antagonist at serotonin 5-HT2A receptors. This multifaceted action helps to rebalance dopamine and serotonin activity in the brain, leading to improvements in mood, thought processes, and overall behavior. Aripiprazole's distinct mechanism contributes to its efficacy across various psychiatric conditions, often with a generally favorable side effect profile compared to some other antipsychotics, particularly regarding metabolic and extrapyramidal symptoms. It is also indicated for the treatment of irritability associated with autistic disorder.

Uses

• Schizophrenia.
• Bipolar I disorder (manic/mixed episodes).
• Adjunctive treatment for major depressive disorder.
• Irritability associated with autistic disorder.

Directions For Use

Take once daily, with or without food, as prescribed by your doctor. Do not stop abruptly.

Benefits

• Manages psychotic symptoms effectively.
• Stabilizes mood in bipolar disorder.
• Enhances antidepressant efficacy.
• Reduces irritability in autism.
• Lower risk of weight gain than some other antipsychotics.
• Generally well-tolerated.

Side Effects

• Nausea
• Vomiting
• Constipation
• Headache
• Dizziness
• Insomnia
• Akathisia (restlessness)
• Anxiety
• Weight gain (less common)
• Tremor
• Blurred vision
• Orthostatic hypotension

Safety Measures

• Alcohol - Avoid alcohol as it can increase sedation and other central nervous system depressant effects.
• Pregnancy - Consult a doctor; use only if potential benefits outweigh risks, as fetal exposure may lead to withdrawal symptoms in newborns.
• Breastfeeding - Not recommended, as aripiprazole passes into breast milk and may affect the infant.
• Liver - Use with caution in patients with liver impairment; dosage adjustment may be necessary.
• Kidney - Use with caution in patients with severe kidney impairment; dosage adjustment may be required.
• Lung - Generally safe for use in patients with lung conditions; no specific contraindications.

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