AZELIREN 8 MG TAB 10

About

Azilsartan is an angiotensin II receptor blocker (ARB) indicated for the treatment of hypertension. It works by selectively blocking the binding of angiotensin II to the AT1 receptor in various tissues, including vascular smooth muscle. This blockade prevents the vasoconstrictive and aldosterone-secreting effects of angiotensin II, leading to vasodilation, reduced peripheral vascular resistance, and decreased blood pressure. Azilsartan provides effective and sustained blood pressure reduction, often with a favorable tolerability profile.

Its mechanism of action helps to protect target organs from the damaging effects of chronic hypertension. Azilsartan is rapidly absorbed after oral administration and has a long half-life, supporting once-daily dosing. It is often used as monotherapy or in combination with other antihypertensive agents to achieve optimal blood pressure control and reduce cardiovascular risk.

Uses

• Treatment of essential hypertension.
• Used alone or in combination with other antihypertensive agents.
• Reduction of cardiovascular risk associated with high blood pressure.
• Management of high blood pressure in adults.

Directions For Use

Take this medication orally once daily, with or without food, as directed by your healthcare provider.

Benefits

• Effectively lowers high blood pressure.
• Provides sustained blood pressure control.
• Reduces risk of cardiovascular events.
• Well-tolerated by many patients.
• Once-daily dosing for convenience.
• Can be combined with other medications.

Side Effects

• Dizziness
• Fatigue
• Diarrhea
• Nausea
• Headache
• Cough (less common than ACE inhibitors)
• Hypotension
• Hyperkalemia (elevated potassium)
• Renal impairment (especially in susceptible patients)
• Back pain
• Peripheral edema
• Angioedema (rare)

Safety Measures

• Alcohol - Alcohol may increase the blood pressure-lowering effect of azilsartan, potentially causing dizziness or lightheadedness.
• Pregnancy - Contraindicated during the second and third trimesters of pregnancy due to risk of fetal injury or death.
• Breastfeeding - Not recommended during breastfeeding as it is unknown if azilsartan is excreted in human milk.
• Liver - Use with caution in patients with severe hepatic impairment; dose adjustment may be considered.
• Kidney - Use with caution in patients with renal artery stenosis or severe renal impairment due to risk of worsening kidney function.
• Lung - Generally safe for use in patients with lung conditions; no specific contraindications related to pulmonary function.

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