Bicatero 50mg Tablet

About

Bicalutamide is a non-steroidal anti-androgen used in the treatment of prostate cancer. It works by competitively binding to androgen receptors in target tissues, thereby preventing androgens (like testosterone and dihydrotestosterone) from stimulating the growth of prostate cancer cells. This action effectively blocks the hormonal signals that drive prostate cancer progression, leading to tumor regression or stabilization. Its mechanism of action is crucial in androgen-dependent prostate cancers. Administered orally, bicalutamide is typically used in combination with luteinizing hormone-releasing hormone (LHRH) analogs or surgical castration as part of maximal androgen blockade (MAB) for advanced prostate cancer. It can also be used as monotherapy in certain situations, particularly for patients who cannot tolerate or prefer to avoid LHRH analogs. Regular monitoring of prostate-specific antigen (PSA) levels and liver function tests is important during treatment to assess efficacy and manage potential adverse effects.

Uses

• Advanced prostate cancer
• Metastatic prostate cancer
• Locally advanced prostate cancer (in combination)
• As monotherapy in specific cases

Directions For Use

Take orally once daily, with or without food, as directed by a physician. Do not crush or chew the tablet.

Benefits

• Effective in treating prostate cancer.
• Oral administration for convenience.
• Can be used in combination with other therapies.
• Helps to reduce tumor size and slow disease progression.
• Improves symptoms associated with prostate cancer.
• Well-established safety profile.

Side Effects

• Hot flashes
• Breast pain and tenderness (gynecomastia)
• Nausea
• Diarrhea
• Constipation
• Fatigue
• Liver enzyme elevation
• Peripheral edema (swelling)
• Anemia
• Rash
• Dizziness
• Weight gain

Safety Measures

• Alcohol - Avoid excessive alcohol consumption as it may increase the risk of liver toxicity.
• Pregnancy - Contraindicated in women, especially during pregnancy, due to potential for fetal harm.
• Breastfeeding - Not applicable as this medication is for male patients.
• Liver - Use with caution in patients with liver impairment; monitor liver function tests closely.
• Kidney - No dose adjustment is typically required in patients with renal impairment.
• Lung - Use with caution in patients with pre-existing lung conditions; monitor for interstitial lung disease.

Disclaimer

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