Biotrexate 500mg Injection

Salt Composition: Methotrexate  
Manufacturer: ZYDUS CADILA  
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About

Biotrexate 500mg Injection contains Methotrexate, an anti-metabolite and immunosuppressant. It is used to treat certain cancers, including acute lymphocytic leukemia (ALL), meningeal leukemia, non-Hodgkin’s lymphoma, osteosarcoma, cutaneous T-cell lymphoma, breast cancer, and head and neck cancers in adults. Additionally, it is prescribed for severe psoriasis (a skin condition causing red, scaly patches) and rheumatoid arthritis in adults.

Avoid using Biotrexate 500mg Injection if you are allergic to methotrexate or any of its components. It should not be taken if you have liver or kidney issues, blood disorders, a weakened immune system, or if you are pregnant or breastfeeding. Inform your doctor immediately if you experience symptoms like coughing or spitting up blood, muscle weakness, vision changes, or cognitive disturbances such as memory loss or disorientation. Methotrexate may affect fertility; effective contraception is advised during treatment and for six months after the final dose.

Let your physician know if you have a history of stomach ulcers, ongoing infections, mild kidney problems, or if you've had any recent vaccinations before beginning therapy. Biotrexate 500mg Injection may cause serious side effects even at low doses, so regular medical checkups and lab tests are essential for safe use.

 Uses 

  • To treat rheumatoid arthritis
  • To treat certain types of cancers
  • To treat severe psoriasis

Directions for use

This medicine should be administered by a doctor or nurse. Please do not attempt to self-administer it.


Side effects 
    

  • Severe allergic reactions
  • Spitting or coughing blood
  • Chest pain
  • Diarrhea, Nausea and Vomiting
  • Decreased WBC and platelet count
  • Dizziness
  • Tiredness, fever, and shivering
  • Weakness on one side of the body
  • Muscle weakness
  • Hairloss
  • Photosensitivity
  • Rash
  • Blurred vision

    
Safety Measures

Alcohol -Consuming alcohol while taking Biotrexate 500mg Injection is unsafe, as it may increase the risk of liver damage.
Pregnancy -Avoid using Biotrexate 500mg Injection during pregnancy, as it may lead to birth defects. Inform your doctor if you are pregnant, think you might be pregnant, or are planning to conceive during treatment. Use reliable birth control throughout the treatment and for six months after your final dose.
Breastfeeding - Breastfeeding is not advised while taking Biotrexate 500mg Injection, as the medication can pass into breast milk in small amounts and may harm your baby. Avoid breastfeeding throughout the treatment period.
Liver - Biotrexate 500mg Injection is not recommended for use in patients with acute liver failure. Dose adjustments may be required in individuals with liver conditions. Inform your doctor about any liver disease before starting the treatment.
Kidney -Biotrexate 500mg Injection should be used with caution in patients with kidney problems, as it may worsen kidney function. Regular monitoring of kidney function is advised during treatment.

  Disclaimer

Med E Hub is committed to delivering reliable, expert-reviewed information to help consumers make informed health decisions. However, the content provided on this website is for informational purposes only and is not intended to replace professional medical advice, diagnosis, or treatment.

Always consult your doctor for any medical concerns, and discuss your questions about health conditions or medications with a qualified healthcare professional. Do not ignore or delay seeking professional medical advice based on information found on Med E Hub.

Our goal is to complement, not replace, the essential doctor-patient reilationshp.

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