About
Cloff 500, containing Ciprofloxacin 500mg, is a potent, broad-spectrum antibiotic belonging to the fluoroquinolone class. Its mechanism of action involves inhibiting bacterial DNA gyrase and topoisomerase IV, two essential enzymes required for bacterial DNA replication, transcription, repair, and recombination. By disrupting these critical processes, Ciprofloxacin effectively leads to bacterial cell death, demonstrating a strong bactericidal effect. It is highly effective against a wide array of Gram-positive and Gram-negative bacteria, making it a versatile choice for treating various severe bacterial infections. Common indications include complicated urinary tract infections, respiratory tract infections (such as pneumonia), skin and soft tissue infections, bone and joint infections, and certain types of gastrointestinal infections. Due to its broad coverage and excellent tissue penetration, Ciprofloxacin remains a cornerstone in the treatment of many serious bacterial pathogens, though its use is carefully considered due to potential side effects.
Uses
- Treatment of urinary tract infections (UTIs).
- Management of respiratory tract infections.
- Treatment of skin and soft tissue infections.
- Therapy for bone and joint infections.
Directions For Use
Take one tablet twice daily, or as directed by your physician. Swallow whole with water; do not crush or chew. Avoid taking with dairy products or antacids.
Benefits
- Broad-spectrum antibacterial activity.
- Effective against many resistant strains.
- Penetrates various body tissues well.
- Oral administration for convenience.
- Rapid onset of action.
- Treats a wide range of severe infections.
Side Effects
- Nausea
- Diarrhea
- Abdominal pain
- Headache
- Dizziness
- Insomnia
- Rash
- Photosensitivity
- Tendonitis/Tendon rupture (rare but serious)
- Peripheral neuropathy (rare)
- QT prolongation (rare)
- Clostridium difficile infection
Safety Measures
- Alcohol - Alcohol may increase the risk of central nervous system side effects like dizziness or lightheadedness. Use with caution.
- Pregnancy - Generally not recommended during pregnancy due to potential risks to fetal cartilage development. Use only if clearly needed and benefits outweigh risks.
- Breastfeeding - Not recommended during breastfeeding as Ciprofloxacin passes into breast milk and may affect the infant's joints.
- Liver - Use with caution in patients with liver impairment; dosage adjustments may be necessary in severe cases.
- Kidney - Dosage adjustment is required in patients with moderate to severe kidney impairment to prevent accumulation and toxicity.
- Lung - Use with caution in patients with a history of QT prolongation or conditions predisposing to arrhythmias, which can affect lung function indirectly.
Disclaimer
MedEHub is committed to delivering reliable, expert-reviewd information to help consumers make informed health decisions. However, the content provided on this website is for informational purposes only and is not intended to replace professional medical advice, diagnosis or treatment.
Always consult your doctor for any medical concerns, and discuss your questions about health conditions or medications with a qualified healthcare professional. Do not ignore or delay seeking professional medical advice based on information found on Med E Hub.
Our goal is to complement, not replace, the essential doctor-patient relationship.
| Shipping Cost |
|
| Shop Location | Assam, India |
No comments found for this product. Be the first to comment!