D 25% 100ML

About

Dextrose 25% solution is a hypertonic intravenous preparation containing 25 grams of dextrose per 100 mL. This concentrated glucose solution is primarily used for the rapid treatment of severe hypoglycemia (low blood sugar) in adults and children, and sometimes in neonates. Its hypertonicity allows for quick elevation of blood glucose levels, making it a critical intervention in emergency settings. It also provides a significant caloric source and can be used in situations requiring concentrated glucose administration, though careful monitoring is essential due to its high osmolarity. This solution is vital for quickly restoring metabolic balance in acute glucose deficiency.

Uses

• Rapid treatment of severe hypoglycemia.
• Management of insulin shock.
• Provision of concentrated caloric support.
• Temporary treatment of hyperkalemia (shifts potassium intracellularly).

Directions For Use

Administer intravenously slowly, usually via a central or large peripheral vein, as directed by a healthcare professional. Dosage depends on the patient's condition and response.

Benefits

• Quickly raises blood glucose levels.
• Provides a concentrated energy source.
• Essential for emergency hypoglycemia.
• Can be life-saving in severe cases.
• Reduces symptoms of low blood sugar.
• Supports metabolic function during critical illness.

Side Effects

• Hyperglycemia and glycosuria.
• Fluid overload, especially in susceptible patients.
• Electrolyte disturbances (e.g., hypokalemia, hyponatremia).
• Local venous irritation, pain, or phlebitis.
• Tissue necrosis if extravasation occurs.
• Rebound hypoglycemia if infusion stopped abruptly.
• Osmotic diuresis leading to dehydration.
• Cerebral edema in certain conditions.
• Fever and infection at injection site.
• Cardiac overload.
• Allergic reactions (rare).
• Hyperosmolar nonketotic state.

Safety Measures

• Alcohol - No direct interaction with alcohol, but alcohol can affect blood sugar levels, so concurrent use should be managed under medical supervision.
• Pregnancy - Use with caution during pregnancy, especially in diabetic mothers, due to the risk of hyperglycemia and potential fetal effects; close monitoring is crucial.
• Breastfeeding - Generally considered safe for use during breastfeeding when clinically indicated. Monitor maternal glucose levels.
• Liver - Use with extreme caution in patients with severe liver impairment, as glucose metabolism is significantly affected; very close blood glucose monitoring is required.
• Kidney - Use with caution in patients with severe kidney impairment due to increased risk of fluid overload, electrolyte imbalances, and altered glucose excretion; close monitoring is essential.
• Lung - Use with caution in patients with severe lung conditions (e.g., pulmonary edema) due to the significant risk of fluid overload exacerbating respiratory distress.

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