DARGEN 40 INJ 1

About

Dargen 40 Injection, containing pantoprazole, is a proton pump inhibitor (PPI) used to reduce stomach acid production. It works by irreversibly binding to the H+/K+-ATPase pump in the gastric parietal cells, thereby inhibiting the final step of acid secretion. This leads to a significant and prolonged reduction in gastric acid, promoting the healing of erosions and ulcers and alleviating symptoms associated with acid-related disorders.

The injectable form is particularly useful for patients who are unable to take oral medication, such as those with severe gastroesophageal reflux disease (GERD), erosive esophagitis, Zollinger-Ellison syndrome, or for the prevention of stress ulcers in critically ill patients. It provides rapid and effective acid suppression, which is vital for managing acute conditions and preventing complications in hospitalized individuals.

Uses

• Treatment of severe erosive esophagitis.
• Management of Zollinger-Ellison syndrome.
• Prevention of re-bleeding in peptic ulcers.
• Short-term treatment of GERD in hospitalized patients.

Directions For Use

Administer intravenously as an infusion over 2-15 minutes, or as a slow intravenous injection, as prescribed by a doctor.

Benefits

• Effectively reduces stomach acid production.
• Promotes healing of esophageal erosions and ulcers.
• Provides rapid symptom relief for acid-related conditions.
• Prevents stress ulcers in critical care settings.
• Suitable for patients unable to take oral medication.
• Long-lasting acid suppression.

Side Effects

• Headache
• Nausea
• Vomiting
• Diarrhea
• Abdominal pain
• Flatulence
• Dizziness
• Rash
• Injection site reactions
• Increased liver enzymes
• Vitamin B12 deficiency (long-term use)
• Bone fractures (long-term use)

Safety Measures

• Alcohol - No direct interaction, but alcohol can irritate the stomach and worsen acid reflux symptoms.
• Pregnancy - Generally considered safe, but use only if clearly needed and under medical supervision.
• Breastfeeding - Small amounts may pass into breast milk; use with caution and monitor the infant.
• Liver - Use with caution in patients with severe hepatic impairment; dosage adjustment may be necessary.
• Kidney - Generally safe for use in patients with kidney conditions; no dosage adjustment typically required.
• Lung - Generally safe for lung conditions; no specific precautions related to respiratory function.

Disclaimer

MedEHub is committed to delivering reliable, expert-reviewd information to help consumers make informed health decisions. However, the content provided on this website is for informational purposes only and is not intended to replace professional medical advice, diagnosis or treatment.

Always consult your doctor for any medical concerns, and discuss your questions about health conditions or medications with a qualified healthcare professional. Do not ignore or delay seeking professional medical advice based on information found on Med E Hub.

Our goal is to complement, not replace, the essential doctor-patient relationship.