Degapride 80mg Injection

About

Degapride Injection is an atypical antipsychotic medication primarily used in the management of various psychiatric disorders. It exerts its therapeutic effects by modulating dopamine and serotonin receptor activity in the brain, specifically acting as a dopamine D2 and serotonin 5-HT2A receptor antagonist. This dual action helps to alleviate positive and negative symptoms of psychosis, stabilize mood, and improve cognitive function.

Its injectable formulation is particularly useful for rapid tranquilization in acute agitation or for long-acting maintenance therapy in patients with adherence challenges, providing consistent therapeutic levels.

Uses

• Treatment of schizophrenia.
• Management of acute manic or mixed episodes of bipolar disorder.
• For rapid tranquilization in acute agitation.
• Maintenance treatment for chronic psychotic disorders.

Directions For Use

Administer intramuscularly by a healthcare professional. Dosage and frequency depend on the specific indication and patient's clinical response.

Benefits

• Effective in reducing psychotic symptoms.
• Helps stabilize mood in bipolar disorder.
• Rapid onset of action for acute agitation.
• Long-acting formulation improves adherence.
• May improve cognitive function.
• Reduces relapse rates in chronic conditions.

Side Effects

• Sedation
• Dizziness
• Weight gain
• Extrapyramidal symptoms (EPS)
• Orthostatic hypotension
• Dry mouth
• Constipation
• Blurred vision
• Increased prolactin levels
• QT prolongation
• Neuroleptic Malignant Syndrome (rare)
• Injection site pain

Safety Measures

• Alcohol - Avoid alcohol as it can enhance central nervous system depression and increase sedation.
• Pregnancy - Use only if clearly indicated and benefits outweigh risks; monitor neonates for withdrawal symptoms.
• Breastfeeding - Not recommended; consult a doctor as the drug may pass into breast milk.
• Liver - Use with caution in hepatic impairment; dose adjustments may be necessary.
• Kidney - Generally safe in mild to moderate renal impairment; monitor in severe cases.
• Lung - Use with caution in patients with respiratory depression or severe lung disease.

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