Degatide 80mg Injection

About

Degatide 80mg Injection is a glucagon-like peptide-1 (GLP-1) receptor agonist indicated for the management of type 2 diabetes mellitus. It mimics the action of natural GLP-1, a hormone that helps regulate blood sugar levels. Degatide stimulates insulin secretion in a glucose-dependent manner, suppresses glucagon secretion, slows gastric emptying, and promotes satiety, leading to improved glycemic control and potential weight loss.

Its multifaceted mechanism addresses several pathophysiological defects in type 2 diabetes, making it an effective agent for achieving target HbA1c levels and reducing cardiovascular risk factors.

Uses

• Management of type 2 diabetes mellitus.
• To improve glycemic control.
• As an adjunct to diet and exercise.
• May reduce the risk of major adverse cardiovascular events.

Directions For Use

Administer subcutaneously once weekly, preferably on the same day each week. Follow your doctor's instructions carefully.

Benefits

• Lowers HbA1c effectively.
• Promotes weight loss.
• Reduces post-meal glucose excursions.
• May offer cardiovascular benefits.
• Convenient once-weekly dosing.
• Glucose-dependent insulin secretion reduces hypoglycemia risk.

Side Effects

• Nausea
• Vomiting
• Diarrhea
• Constipation
• Abdominal pain
• Injection site reactions
• Headache
• Dizziness
• Fatigue
• Hypoglycemia (when used with sulfonylurea/insulin)
• Pancreatitis (rare)
• Gallstones (rare)

Safety Measures

• Alcohol - Limit alcohol intake as it can affect blood sugar levels and potentially increase the risk of pancreatitis.
• Pregnancy - Not recommended during pregnancy; switch to insulin if pregnancy occurs or is planned.
• Breastfeeding - Avoid during breastfeeding as it is unknown if the drug passes into breast milk.
• Liver - Generally safe in mild to moderate hepatic impairment; use with caution in severe cases.
• Kidney - Use with caution in severe renal impairment or end-stage renal disease; dose adjustment may be needed.
• Lung - No specific precautions for lung conditions; generally considered safe.

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