DEXACORT N E/D 10ML

About

DEXACORT N E/D is a combination ophthalmic/otic preparation containing Dexamethasone, a potent corticosteroid, and Neomycin, an aminoglycoside antibiotic. Dexamethasone provides anti-inflammatory and immunosuppressive effects, reducing swelling, redness, itching, and allergic reactions in the eye or ear. It works by inhibiting the release of inflammatory mediators and suppressing the immune response.

Neomycin is included to provide broad-spectrum antibacterial coverage against susceptible Gram-positive and Gram-negative bacteria that commonly cause ocular or otic infections. This combination is particularly useful in treating inflammatory conditions of the eye or ear where there is a risk or presence of bacterial infection. Proper administration is crucial to minimize systemic absorption and potential side effects.

Uses

• Treatment of inflammatory conditions of the eye (e.g., conjunctivitis, keratitis).
• Management of inflammatory conditions of the ear (e.g., otitis externa).
• Post-operative inflammation and infection prophylaxis in ocular surgery.
• Allergic conjunctivitis with bacterial infection risk.

Directions For Use

Instill the prescribed number of drops into the affected eye or ear.
Wash hands before and after use; avoid touching the dropper tip to any surface.

Benefits

• Reduces inflammation and swelling.
• Provides antibacterial coverage.
• Relieves itching and discomfort.
• Effective for various eye and ear infections.
• Dual action for inflammatory-infectious conditions.
• Convenient topical administration.

Side Effects

• Temporary stinging or burning upon instillation
• Blurred vision (ocular use)
• Increased intraocular pressure (prolonged ocular use)
• Cataract formation (prolonged ocular use)
• Allergic reactions (e.g., itching, rash)
• Superinfection (with prolonged use)
• Delayed wound healing
• Corneal thinning (ocular use)
• Ototoxicity (rare, with perforated eardrum in otic use)
• Adrenal suppression (very rare, with extensive systemic absorption)
• Pupil dilation
• Ptosis

Safety Measures

• Alcohol - No known direct interaction with topical application. Systemic absorption is minimal.
• Pregnancy - Use with caution. Consult a physician. Systemic absorption is low, but potential risks to the fetus from corticosteroids should be considered.
• Breastfeeding - Minimal systemic absorption, so unlikely to pose significant risk to breastfed infant. Consult a healthcare provider.
• Liver - Minimal systemic absorption, so liver conditions are generally not a concern. No dose adjustment needed.
• Kidney - Minimal systemic absorption, so kidney conditions are generally not a concern. No dose adjustment needed.
• Lung - No specific contraindications related to lung conditions, as systemic absorption is negligible.

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