DEXTROSE 25% 100ML 1X100

About

Dextrose 25% (D25W) is a highly concentrated, hypertonic intravenous solution specifically formulated for the rapid and effective treatment of acute hypoglycemia, particularly in infants and children, or in adult patients requiring a more potent and immediate glucose boost. Its elevated concentration delivers a substantial caloric load and swiftly elevates blood glucose levels, making it a critical intervention in emergency medical settings to reverse severe hypoglycemic states and mitigate the risk of irreversible neurological damage. Due to its significant hypertonicity, D25W must be administered with extreme caution, typically via a central or large peripheral vein, and under strict medical supervision to prevent potential complications such as local vein irritation, phlebitis, or tissue necrosis if extravasation occurs. Careful monitoring of blood glucose and electrolytes is essential during and after administration.

Uses

• Rapid treatment of hypoglycemia.
• Source of concentrated calories.
• Management of acute energy deficits.
• Used in pediatric emergencies for glucose support.

Directions For Use

Administer intravenously, usually via a central or large peripheral vein, slowly and under strict medical supervision. Dosage is individualized based on patient needs.

Benefits

• Rapidly reverses hypoglycemia.
• Provides significant caloric support.
• Prevents neurological complications from low blood sugar.
• Essential in emergency situations.
• Small volume for high glucose delivery.
• Supports metabolic needs.

Side Effects

• Hyperglycemia (if not monitored).
• Local vein irritation/phlebitis.
• Extravasation leading to tissue necrosis.
• Osmotic diuresis.
• Fluid overload.
• Hypokalemia (due to intracellular shift).
• Rebound hypoglycemia (if discontinued abruptly).
• Fever.
• Infection at injection site.
• Allergic reactions.
• Electrolyte imbalances.
• Cerebral edema (in specific conditions).

Safety Measures

• Alcohol - No direct interaction; however, alcohol can cause hypoglycemia, so D25W may be used to treat alcohol-induced hypoglycemia.
• Pregnancy - Use with caution and only when clearly indicated for severe maternal hypoglycemia, under strict medical supervision.
• Breastfeeding - Use with caution and only when clearly indicated for severe maternal hypoglycemia, under strict medical supervision.
• Liver - Use with caution in severe liver impairment; monitor blood glucose closely as liver plays a key role in glucose metabolism.
• Kidney - Use with caution in severe renal impairment due to risk of fluid overload and electrolyte disturbances; monitor closely.
• Lung - Administer cautiously in patients with pulmonary edema or conditions predisposing to fluid overload.

Disclaimer

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