Docefect RTU 80mg Injection

About

Docetaxel, a taxane antineoplastic agent, is a crucial chemotherapy drug used in the treatment of various solid tumors. It exerts its cytotoxic effects by promoting the assembly of microtubules from tubulin dimers and inhibiting their depolymerization, leading to the stabilization of microtubules. This action disrupts the normal dynamic reorganization of the microtubule network, which is essential for vital cellular functions such as mitosis and interphase cellular processes. Consequently, docetaxel induces cell cycle arrest at the G2/M phase and triggers apoptosis in rapidly dividing cancer cells, thereby inhibiting tumor growth and proliferation.

Its mechanism of action makes it effective against a broad spectrum of malignancies, often employed either as a monotherapy or in combination with other chemotherapeutic agents or targeted therapies. The drug is administered intravenously and requires careful monitoring due to its potent effects on cellular processes.

Uses

• Treatment of breast cancer
• Management of non-small cell lung cancer
• Therapy for hormone-refractory prostate cancer
• Treatment of gastric adenocarcinoma

Directions For Use

Administered intravenously by a qualified healthcare professional. Dosage and schedule are determined by the specific cancer type, patient's body surface area, and overall health.

Benefits

• Effective against a wide range of solid tumors.
• Can significantly improve progression-free survival.
• Often used in effective combination chemotherapy regimens.
• Helps in reducing tumor size and burden.
• May alleviate cancer-related symptoms.
• Provides a vital treatment option for advanced malignancies.

Side Effects

• Bone marrow suppression (neutropenia)
• Peripheral neuropathy (numbness, tingling)
• Fluid retention (edema)
• Nausea and vomiting
• Diarrhea
• Hair loss (alopecia)
• Fatigue and weakness
• Muscle and joint pain (myalgia, arthralgia)
• Skin reactions (rash, redness)
• Nail changes (discoloration, brittleness)
• Hypersensitivity reactions (allergic reactions)
• Oral mucositis (mouth sores)

Safety Measures

• Alcohol - Avoid alcohol consumption as it may exacerbate certain side effects or interact with the medication.
• Pregnancy - Not recommended during pregnancy due to potential fetal harm; effective contraception is advised for patients of childbearing potential.
• Breastfeeding - Contraindicated during breastfeeding as the drug may pass into breast milk and pose risks to the infant.
• Liver - Use with caution in patients with liver impairment; dose adjustments may be necessary due to altered drug metabolism.
• Kidney - Use with caution in patients with kidney impairment; close monitoring is recommended, though renal excretion is a minor elimination pathway.
• Lung - Monitor for signs of pulmonary toxicity, such as interstitial pneumonitis, especially in patients with pre-existing lung conditions.

Disclaimer

MedEHub is committed to delivering reliable, expert-reviewd information to help consumers make informed health decisions. However, the content provided on this website is for informational purposes only and is not intended to replace professional medical advice, diagnosis or treatment.

Always consult your doctor for any medical concerns, and discuss your questions about health conditions or medications with a qualified healthcare professional. Do not ignore or delay seeking professional medical advice based on information found on Med E Hub.

Our goal is to complement, not replace, the essential doctor-patient relationship.