Dutaxel 100mg Injection

About

Dutaxel 100mg Injection is a potent antineoplastic agent belonging to the taxane class of chemotherapy drugs. Its primary mechanism of action involves promoting the assembly of microtubules from tubulin dimers and inhibiting their depolymerization, leading to the stabilization of microtubules. This disruption of the dynamic equilibrium of the microtubule network is essential for vital cellular functions, including mitosis and interphase processes. Consequently, Dutaxel arrests cells in the G2/M phase of the cell cycle, preventing cell division and ultimately inducing apoptosis in cancer cells.

Administered intravenously, Dutaxel is a critical component in the treatment of various solid tumors. Its efficacy is attributed to its ability to interfere with the cellular machinery responsible for cell proliferation, making it effective against rapidly dividing cancer cells. Due to its potent nature, treatment with Dutaxel requires careful monitoring for potential side effects and is typically managed by oncology specialists.

Uses

• Treatment of breast cancer
• Management of non-small cell lung cancer
• Therapy for prostate cancer
• Treatment of gastric adenocarcinoma

Directions For Use

This injection is administered intravenously by a qualified healthcare professional, often with premedication, in a clinical setting.

Benefits

• Effective against a range of solid tumors
• Improves progression-free and overall survival
• Can be used in metastatic disease
• Part of combination chemotherapy regimens
• Reduces tumor size and disease burden
• Offers palliative benefits in advanced cancers

Side Effects

• Myelosuppression (low blood counts)
• Fluid retention (edema)
• Hair loss (alopecia)
• Nausea and vomiting
• Fatigue and asthenia
• Peripheral neuropathy (numbness/tingling)
• Skin reactions (rash, desquamation)
• Nail changes
• Hypersensitivity reactions
• Diarrhea
• Muscle and joint pain (arthralgia/myalgia)
• Mucositis (inflammation of mucous membranes)

Safety Measures

• Alcohol - Avoid or limit alcohol consumption due to potential for increased liver toxicity and general debilitation during chemotherapy.
• Pregnancy - Contraindicated; Dutaxel is highly teratogenic and fetotoxic, causing severe harm to the developing fetus.
• Breastfeeding - Contraindicated; the drug passes into breast milk and can cause serious adverse effects in the nursing infant.
• Liver - Dose adjustment is required in patients with liver impairment due to hepatic metabolism; increased risk of toxicity.
• Kidney - Use with caution; dose adjustment may be necessary in patients with severe renal impairment.
• Lung - Can cause interstitial pneumonitis or acute respiratory distress syndrome; monitor respiratory function and symptoms.

Disclaimer

MedEHub is committed to delivering reliable, expert-reviewd information to help consumers make informed health decisions. However, the content provided on this website is for informational purposes only and is not intended to replace professional medical advice, diagnosis or treatment.

Always consult your doctor for any medical concerns, and discuss your questions about health conditions or medications with a qualified healthcare professional. Do not ignore or delay seeking professional medical advice based on information found on Med E Hub.

Our goal is to complement, not replace, the essential doctor-patient relationship.