ELIGARD 45 MG INJ

About

ELIGARD (Leuprolide acetate) is a gonadotropin-releasing hormone (GnRH) agonist. It works by initially stimulating, then continuously down-regulating, the GnRH receptors in the pituitary gland. This sustained down-regulation leads to a significant decrease in the secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH), which in turn reduces the production of testosterone in men and estrogen in women. This hormonal suppression is therapeutically beneficial in hormone-sensitive conditions.

ELIGARD is administered as a subcutaneous injection, typically as a depot formulation that provides sustained release of leuprolide over an extended period. Its primary clinical application is in the management of advanced prostate cancer, where it helps to reduce testosterone levels, thereby slowing tumor growth. It is also used in other hormone-dependent conditions such as endometriosis and uterine fibroids.

Uses

• Advanced prostate cancer
• Endometriosis
• Uterine fibroids
• Central precocious puberty

Directions For Use

Administered as a subcutaneous injection by a healthcare professional. The injection site should be rotated regularly. Follow your doctor's prescribed schedule.

Benefits

• Effectively suppresses testosterone levels in men
• Helps manage symptoms of advanced prostate cancer
• Reduces estrogen levels in women for endometriosis/fibroids
• Long-acting formulation reduces frequency of injections
• Can improve quality of life in hormone-sensitive conditions
• Established efficacy in hormonal therapy

Side Effects

• Hot flashes
• Injection site reactions (pain, redness, swelling)
• Fatigue and weakness
• Decreased libido
• Erectile dysfunction (men)
• Bone density loss (long-term use)
• Mood changes, depression
• Headache
• Nausea
• Breast tenderness or swelling
• Weight changes
• Muscle weakness

Safety Measures

• Alcohol - No specific contraindication with alcohol, but excessive intake may worsen hot flashes or mood changes.
• Pregnancy - Contraindicated in pregnancy due to potential fetal harm. Effective contraception is required for women of childbearing potential.
• Breastfeeding - Breastfeeding is not recommended during treatment due to potential hormonal effects on the infant.
• Liver - Use with caution in patients with pre-existing liver impairment. Liver function should be monitored periodically.
• Kidney - Use with caution in patients with pre-existing renal impairment. No specific dose adjustment is typically required, but monitoring is advisable.
• Lung - No specific contraindication related to lung conditions. Monitor for any new or worsening respiratory symptoms, though rare.

Disclaimer

MedEHub is committed to delivering reliable, expert-reviewd information to help consumers make informed health decisions. However, the content provided on this website is for informational purposes only and is not intended to replace professional medical advice, diagnosis or treatment.

Always consult your doctor for any medical concerns, and discuss your questions about health conditions or medications with a qualified healthcare professional. Do not ignore or delay seeking professional medical advice based on information found on Med E Hub.

Our goal is to complement, not replace, the essential doctor-patient relationship.