EMPAGLOXIT 25 10S

About

Empagloxit 25 contains empagliflozin, an advanced oral antidiabetic medication classified as a sodium-glucose co-transporter 2 (SGLT2) inhibitor. This innovative drug works by selectively blocking the SGLT2 protein in the kidneys, which is responsible for reabsorbing glucose back into the bloodstream. By inhibiting SGLT2, empagliflozin promotes the excretion of excess glucose into the urine, thereby effectively lowering blood glucose levels in a manner independent of insulin. This unique mechanism makes it a powerful tool in the management of type 2 diabetes mellitus, used as an adjunct to diet and exercise. Beyond its primary glucose-lowering effects, empagliflozin has demonstrated remarkable benefits in reducing the risk of major cardiovascular events, including cardiovascular death and hospitalization for heart failure, in patients with type 2 diabetes and established cardiovascular disease. Furthermore, it has shown significant promise in slowing the progression of chronic kidney disease in this patient population, highlighting its multifaceted therapeutic advantages.

Uses

• Treatment of type 2 diabetes mellitus.
• To reduce the risk of cardiovascular death in adults with type 2 diabetes and established cardiovascular disease.
• To reduce the risk of hospitalization for heart failure in adults with type 2 diabetes and heart failure.
• To reduce the risk of kidney disease progression in adults with type 2 diabetes and chronic kidney disease.

Directions For Use

Take once daily in the morning, with or without food, as prescribed by your doctor. Swallow the tablet whole with water.

Benefits

• Effectively lowers blood glucose levels.
• Reduces risk of cardiovascular death.
• Decreases hospitalization for heart failure.
• Slows progression of kidney disease.
• Promotes modest weight loss.
• Low risk of hypoglycemia when used alone.

Side Effects

• Urinary tract infections (UTIs).
• Genital yeast infections.
• Increased urination.
• Thirst.
• Nausea.
• Constipation.
• Dizziness.
• Hypotension (low blood pressure).
• Ketoacidosis (rare but serious).
• Kidney problems (rare).
• Fournier's gangrene (very rare).
• Back pain.

Safety Measures

• Alcohol - Limit alcohol intake as it can increase the risk of dehydration and lactic acidosis, especially when combined with other diabetes medications.
• Pregnancy - Not recommended during pregnancy, especially in the second and third trimesters, due to potential adverse effects on fetal kidney development.
• Breastfeeding - Not recommended during breastfeeding as it may pass into breast milk and affect the infant; consult a doctor.
• Liver - Generally safe for use in mild to moderate liver impairment; however, caution is advised, and monitoring may be necessary.
• Kidney - Not recommended for patients with severe kidney impairment (eGFR <30 mL/min/1.73m²); dose adjustment may be needed for moderate impairment.
• Lung - No specific lung-related contraindications; however, ensure adequate hydration to prevent complications.

Disclaimer

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