ERYPRO PREFIL 4000 1

About

ERYPRO PREFIL 4000 contains recombinant human erythropoietin (rHuEPO), a glycoprotein hormone that plays a vital role in stimulating the production of red blood cells in the bone marrow. It functions by mimicking the action of natural erythropoietin, which is primarily produced by the kidneys and is the principal regulator of erythropoiesis. This medication is critically important for the management of anemia, particularly that associated with chronic kidney disease, certain cancer treatments, and other conditions where the body's natural red blood cell production is impaired. By increasing hemoglobin levels, ERYPRO PREFIL 4000 helps to improve oxygen-carrying capacity, reduce the need for blood transfusions, and enhance the overall quality of life for patients.

Uses

• Anemia of chronic kidney disease
• Anemia in cancer patients receiving chemotherapy
• Anemia in HIV-infected patients treated with zidovudine
• Reduction of allogeneic blood transfusions in surgery

Directions For Use

Administer subcutaneously or intravenously as directed by a healthcare professional. Dosage is individualized based on patient weight and hemoglobin levels.

Benefits

• Increases red blood cell count
• Reduces need for blood transfusions
• Improves energy levels and quality of life
• Manages anemia effectively
• Supports oxygen transport
• Prevents anemia-related complications

Side Effects

• Hypertension
• Headache
• Fever
• Nausea
• Vomiting
• Diarrhea
• Injection site pain
• Thrombotic events (e.g., DVT, stroke)
• Seizures
• Allergic reactions
• Pure red cell aplasia (rare)
• Flu-like symptoms

Safety Measures

• Alcohol - No specific interaction with alcohol is known, but general health advice to limit alcohol applies, especially with underlying conditions.
• Pregnancy - Use only if clearly needed and potential benefits outweigh risks; consult a doctor, as animal studies show some adverse effects.
• Breastfeeding - Exercise caution; it is unknown if erythropoietin is excreted in human milk, so consult a physician.
• Liver - Use with caution in patients with severe liver disease; monitor liver function, though primary metabolism is not hepatic.
• Kidney - Primarily used for anemia of chronic kidney disease; dosage adjustments are not typically needed for renal impairment itself.
• Lung - Generally safe; however, monitor for signs of pulmonary embolism, a potential thrombotic complication.

Disclaimer

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