About
Etoricoxib is a highly selective cyclooxygenase-2 (COX-2) inhibitor, belonging to the class of non-steroidal anti-inflammatory drugs (NSAIDs). Its primary mechanism of action involves selectively blocking the COX-2 enzyme, which is predominantly responsible for the synthesis of prostaglandins that mediate pain, inflammation, and fever, particularly at sites of injury or disease. By specifically targeting COX-2, Etoricoxib aims to provide potent anti-inflammatory and analgesic effects while potentially reducing the gastrointestinal side effects, such as ulcers and bleeding, commonly associated with non-selective NSAIDs that inhibit both COX-1 and COX-2. It is widely prescribed for the symptomatic relief of various inflammatory and painful conditions, including osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, and acute gouty arthritis. Its efficacy in managing chronic pain and inflammation makes it a valuable therapeutic option for patients requiring sustained relief.
Uses
- Relief of symptoms of osteoarthritis.
- Treatment of rheumatoid arthritis.
- Management of ankylosing spondylitis.
- Acute pain relief, including dental pain.
Directions For Use
Take one tablet once daily with or without food, as directed by your physician. Do not exceed the prescribed dose.
Benefits
- Effective pain relief.
- Reduces inflammation and swelling.
- Improves joint mobility.
- Potentially lower GI side effect risk than non-selective NSAIDs.
- Long-lasting action, often once daily dosing.
- Useful for chronic inflammatory conditions.
Side Effects
- Abdominal pain
- Diarrhea
- Nausea
- Headache
- Dizziness
- Edema (fluid retention)
- Hypertension (high blood pressure)
- Heartburn
- Fatigue
- Flu-like symptoms
- Palpitations
- Gastric ulcers (less common but possible)
Safety Measures
- Alcohol - Avoid excessive alcohol consumption as it may increase the risk of gastrointestinal irritation and bleeding when taken with Etoricoxib.
- Pregnancy - Not recommended during pregnancy, especially in the third trimester, due to potential risks to the fetus. Consult a doctor.
- Breastfeeding - Not recommended during breastfeeding as Etoricoxib may pass into breast milk. Consult a doctor.
- Liver - Use with caution in patients with mild to moderate liver impairment; contraindicated in severe liver disease.
- Kidney - Use with caution in patients with kidney impairment, as NSAIDs can worsen renal function. Regular monitoring is advised.
- Lung - Use with caution in patients with asthma, as NSAIDs can sometimes trigger bronchospasm.
Disclaimer
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Always consult your doctor for any medical concerns, and discuss your questions about health conditions or medications with a qualified healthcare professional. Do not ignore or delay seeking professional medical advice based on information found on Med E Hub.
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