EXOFERRIC S-200 AMP

About

Exoferric S-200 is an intravenous iron preparation designed to replenish iron stores in patients with iron deficiency anemia who cannot tolerate or adequately respond to oral iron therapy. Iron is an essential component of hemoglobin, myoglobin, and various enzymes, playing a critical role in oxygen transport and cellular respiration. When administered intravenously, the iron complex is taken up by the reticuloendothelial system, where iron is released and incorporated into transferrin, then transported to the bone marrow for erythropoiesis.

This formulation provides a rapid and efficient way to deliver iron directly into the bloodstream, bypassing the gastrointestinal tract and overcoming issues of malabsorption or intolerance. This leads to a quicker increase in hemoglobin levels and replenishment of iron stores, improving symptoms of anemia such as fatigue and shortness of breath. The specific formulation ensures controlled release and minimizes the risk of free iron toxicity, making it a valuable option for severe or refractory iron deficiency.

Uses

• Treatment of iron deficiency anemia in chronic kidney disease patients.
• Treatment of iron deficiency anemia in inflammatory bowel disease.
• Treatment of iron deficiency anemia in patients undergoing hemodialysis.
• Treatment of iron deficiency anemia in patients intolerant to oral iron.

Directions For Use

Administer intravenously by a healthcare professional as a slow injection or infusion. Dosage and frequency are determined by your doctor based on your iron status.

Benefits

• Rapidly replenishes iron stores and increases hemoglobin levels.
• Bypasses gastrointestinal absorption issues and intolerance.
• Effective for patients with severe iron deficiency anemia.
• Reduces the need for blood transfusions in some cases.
• Convenient administration in a clinical setting.
• Improves energy levels and reduces fatigue associated with anemia.

Side Effects

• Nausea
• Vomiting
• Diarrhea
• Constipation
• Headache
• Dizziness
• Hypotension (low blood pressure)
• Injection site reactions (pain, swelling)
• Allergic reactions (rash, itching)
• Flushing
• Muscle cramps
• Taste perversion

Safety Measures

• Alcohol - No specific contraindication with alcohol, but excessive alcohol use can impair iron absorption and liver function, which may complicate anemia management.
• Pregnancy - Generally considered safe and effective for treating iron deficiency anemia in pregnancy, especially in the second and third trimesters, when oral iron is insufficient or not tolerated.
• Breastfeeding - Iron is naturally present in breast milk. Intravenous iron is generally considered safe during breastfeeding as it does not significantly increase iron levels in breast milk.
• Liver - Use with caution in patients with liver impairment, especially those with iron overload conditions (e.g., hemochromatosis). Monitor liver function.
• Kidney - Often used in patients with chronic kidney disease. No specific dose adjustment is typically needed for renal impairment, but monitor iron parameters closely.
• Lung - No specific contraindication. However, severe allergic reactions can manifest with respiratory symptoms; monitor patients during and after administration.

Disclaimer

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