GRANITERO 3 MG INJ VIAL

About

GRANITERO 3 MG INJ VIAL contains Granisetron, a selective 5-hydroxytryptamine-3 (5-HT3) receptor antagonist. This medication works by blocking serotonin, a natural substance in the body that can cause nausea and vomiting. It is primarily used to prevent and treat nausea and vomiting associated with cancer chemotherapy and radiation therapy.

Granisetron acts centrally and peripherally to inhibit the emetic reflex. By blocking 5-HT3 receptors, particularly in the chemoreceptor trigger zone (CTZ) and vagal afferent nerves in the gastrointestinal tract, it effectively reduces the incidence and severity of chemotherapy-induced nausea and vomiting (CINV) and post-operative nausea and vomiting (PONV). Its rapid onset of action and sustained effect make it a valuable agent in supportive care for oncology patients.

Uses

• Prevention of chemotherapy-induced nausea and vomiting.
• Treatment of chemotherapy-induced nausea and vomiting.
• Prevention of radiation therapy-induced nausea and vomiting.
• Prevention of post-operative nausea and vomiting.

Directions For Use

This medication is administered intravenously by a healthcare professional. The dosage and timing depend on the specific chemotherapy regimen or procedure.

Benefits

• Highly effective in preventing nausea and vomiting.
• Reduces discomfort associated with cancer treatments.
• Improves patient quality of life during chemotherapy.
• Rapid onset of action for quick relief.
• Can be used for both acute and delayed CINV.
• Well-tolerated by most patients.

Side Effects

• Headache
• Constipation
• Diarrhea
• Asthenia (weakness)
• Dizziness
• Insomnia
• Abdominal pain
• Fever
• Anxiety
• Bradycardia (slow heart rate)
• Hypotension (low blood pressure)
• Allergic reactions (rare)

Safety Measures

• Alcohol - No known direct interaction, but alcohol can exacerbate nausea and vomiting, so it's best to avoid it.
• Pregnancy - Use only if clearly needed. Animal studies do not indicate direct harmful effects, but human data are limited. Consult your doctor.
• Breastfeeding - It is unknown if Granisetron is excreted in human milk. Caution should be exercised, and a doctor's advice sought.
• Liver - No dose adjustment is generally needed for mild to moderate hepatic impairment. Use with caution in severe liver disease.
• Kidney - No dose adjustment is typically required for renal impairment.
• Lung - No specific lung-related precautions are generally needed.

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