INVOKANA 100 MG 10'S

About

Invokana (Canagliflozin) 100 mg is a potent sodium-glucose co-transporter 2 (SGLT2) inhibitor specifically designed to improve glycemic control in adults diagnosed with type 2 diabetes. Its mechanism involves blocking the reabsorption of glucose in the kidneys, leading to increased glucose excretion in the urine and a subsequent reduction in blood glucose levels. Beyond its primary role in glucose management, canagliflozin has demonstrated significant and clinically meaningful benefits in reducing the risk of major adverse cardiovascular events, including cardiovascular death, non-fatal myocardial infarction, and non-fatal stroke, in patients with type 2 diabetes and established cardiovascular disease. Furthermore, it helps to reduce the risk of hospitalization for heart failure and slows the progression of kidney disease, offering comprehensive protection for vulnerable patients.

Uses

• Management of type 2 diabetes mellitus.
• To reduce the risk of major adverse cardiovascular events in adults with type 2 diabetes and established cardiovascular disease.
• To reduce the risk of end-stage kidney disease, cardiovascular death, and hospitalization for heart failure in adults with type 2 diabetes and chronic kidney disease.
• To reduce the risk of hospitalization for heart failure in adults with type 2 diabetes.

Directions For Use

Take orally once daily, preferably before the first meal of the day, as directed by your doctor.

Benefits

• Effective blood sugar reduction.
• Lowered HbA1c levels.
• Promotes weight loss.
• Reduces cardiovascular risk.
• Slows progression of kidney disease.
• Low risk of hypoglycemia as monotherapy.

Side Effects

• Urinary tract infections
• Genital yeast infections
• Increased urination
• Thirst
• Constipation
• Nausea
• Fatigue
• Dizziness
• Hypotension (especially at initiation)
• Ketoacidosis (rare)
• Fractures (rare)
• Amputation (rare, primarily toe/foot)

Safety Measures

• Alcohol - Moderate alcohol consumption is generally acceptable, but excessive intake may increase the risk of dehydration or ketoacidosis.
• Pregnancy - Not recommended during pregnancy, especially in the second and third trimesters. Consult your doctor.
• Breastfeeding - Not recommended during breastfeeding as it may pass into breast milk. Consult your doctor.
• Liver - Generally safe, but use with caution in severe hepatic impairment as data are limited.
• Kidney - Contraindicated in severe renal impairment or end-stage renal disease. Dose adjustment is necessary for moderate renal impairment.
• Lung - Generally safe, no specific contraindications related to lung conditions.

Disclaimer

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