KETOGRACE TABLET 10

About

KETOGRACE Tablet contains Ketoconazole, an imidazole antifungal agent used to treat various fungal infections. It works by inhibiting the synthesis of ergosterol, a vital component of fungal cell membranes. This disruption leads to increased permeability of the fungal cell membrane, causing leakage of cellular contents and ultimately fungal cell death. Ketoconazole is effective against a broad spectrum of fungi, including dermatophytes, yeasts, and other pathogenic fungi.

While primarily used topically due to concerns about systemic side effects, oral ketoconazole is reserved for serious fungal infections when other antifungal treatments are either ineffective or not tolerated. It is crucial to monitor liver function during systemic treatment with ketoconazole due to its potential for hepatotoxicity. The medication's antifungal action helps to clear infections and alleviate associated symptoms like itching, redness, and scaling.

Uses

• Treatment of systemic fungal infections
• Management of chronic mucocutaneous candidiasis
• Treatment of severe dermatophyte infections
• Off-label use for Cushing's syndrome (due to adrenal enzyme inhibition)

Directions For Use

Take orally with food, as prescribed by your doctor. Follow the full course of treatment.

Benefits

• Broad-spectrum antifungal activity
• Effective against various fungal pathogens
• Can treat severe and systemic infections
• Available in oral form for systemic action
• Helps alleviate symptoms of fungal infections
• May be used in specific endocrine disorders

Side Effects

• Nausea
• Vomiting
• Abdominal pain
• Diarrhea
• Headache
• Dizziness
• Itching
• Rash
• Liver enzyme elevation
• Hepatotoxicity (severe liver damage)
• Adrenal insufficiency
• Gynecomastia (in males)

Safety Measures

• Alcohol - Avoid alcohol consumption as it can increase the risk of liver damage and may worsen gastrointestinal side effects.
• Pregnancy - Generally not recommended during pregnancy due to potential teratogenic effects; use only if benefits outweigh risks.
• Breastfeeding - Ketoconazole is excreted in breast milk. Avoid use during breastfeeding or consult your doctor for alternatives.
• Liver - Contraindicated in patients with acute or chronic liver disease due to significant risk of hepatotoxicity. Close monitoring is essential.
• Kidney - Use with caution in patients with kidney impairment; dosage adjustments may be necessary.
• Lung - Generally safe for use in patients with lung conditions, but caution with co-existing liver issues.

Disclaimer

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