LPS 300SR 10'S

About

LPS 300SR, likely containing Gabapentin 300mg in a sustained-release (SR) formulation, is an anticonvulsant and neuropathic pain medication. Gabapentin is structurally related to the neurotransmitter GABA but does not directly bind to GABA receptors. Its precise mechanism of action is not fully understood but is thought to involve binding to the alpha-2-delta subunit of voltage-gated calcium channels in the central nervous system. This binding modulates the release of excitatory neurotransmitters, thereby reducing neuronal excitability and pain signaling.

The sustained-release formulation allows for less frequent dosing, which can improve patient adherence and provide more consistent therapeutic levels throughout the day. It is particularly effective in managing chronic neuropathic pain conditions, such as postherpetic neuralgia and diabetic neuropathy, where conventional analgesics may be insufficient. It is also used as an adjunctive therapy in the treatment of partial seizures in epilepsy. The SR formulation aims to minimize fluctuations in drug levels, potentially reducing peak-related side effects and improving overall tolerability.

Uses

• Management of neuropathic pain (e.g., postherpetic neuralgia)
• Adjunctive therapy for partial seizures in epilepsy
• Treatment of restless legs syndrome
• Relief of pain associated with diabetic neuropathy

Directions For Use

Take LPS 300SR exactly as prescribed by your doctor, usually once or twice daily, with or without food.

Benefits

• Effective relief from neuropathic pain
• Reduces seizure frequency in epilepsy
• Sustained-release for consistent drug levels
• Less frequent dosing for improved adherence
• May improve sleep quality in pain patients
• Generally well-tolerated with careful titration

Side Effects

• Dizziness
• Drowsiness
• Fatigue
• Ataxia (impaired coordination)
• Peripheral edema
• Nausea
• Vomiting
• Tremor
• Blurred vision
• Weight gain
• Dry mouth
• Memory loss

Safety Measures

• Alcohol - Avoid alcohol consumption as it can enhance the sedative effects of Gabapentin, leading to increased drowsiness and impaired coordination.
• Pregnancy - Consult your doctor. Gabapentin should only be used if the potential benefit justifies the potential risk to the fetus.
• Breastfeeding - Use with caution. Gabapentin is excreted in breast milk and may cause sedation in the infant. Discuss with your doctor.
• Liver - Generally considered safe in patients with liver conditions, as it is primarily excreted unchanged by the kidneys.
• Kidney - Dose adjustment is necessary in patients with impaired kidney function, as Gabapentin is renally excreted.
• Lung - Use with caution in patients with severe respiratory conditions, as it can cause respiratory depression, especially when combined with other CNS depressants.

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