MEGAHENZ-40 TAB 3X10

About

Megahenz-40 Tablet, likely containing Megestrol Acetate 40mg, is a synthetic progestin hormone primarily used in the palliative treatment of advanced breast cancer and endometrial cancer. It works by altering the hormonal environment in the body, which can inhibit the growth of hormone-sensitive cancer cells. In breast cancer, it is thought to exert its antineoplastic effects by interfering with estrogen receptors and inhibiting the release of gonadotropins from the pituitary gland. For endometrial cancer, it directly affects the endometrial lining, promoting differentiation and reducing proliferation.

Beyond its use in oncology, Megestrol Acetate is also widely prescribed as an appetite stimulant to manage cachexia (severe weight loss and muscle wasting) in patients with AIDS and advanced cancer. Its ability to increase appetite and promote weight gain can significantly improve the quality of life for patients experiencing severe wasting syndromes. The mechanism for appetite stimulation is not fully understood but is thought to involve hypothalamic effects.

Uses

• Palliative treatment of advanced breast cancer
• Management of advanced endometrial cancer
• Appetite stimulation in AIDS-related cachexia
• Treatment of anorexia and weight loss in advanced cancer patients

Directions For Use

Take Megahenz-40 Tablet orally as directed by your physician, with or without food.

Benefits

• Helps control the progression of certain cancers
• Effective in stimulating appetite
• Promotes weight gain in cachectic patients
• Improves quality of life in advanced disease
• Oral administration for convenience
• May reduce tumor size or slow growth

Side Effects

• Weight gain
• Nausea
• Vomiting
• Diarrhea
• Constipation
• Breakthrough bleeding
• Hot flashes
• Fluid retention
• Thromboembolic events
• Adrenal suppression
• Headache
• Insomnia

Safety Measures

• Alcohol - No specific contraindication, but excessive alcohol use should be avoided as it may exacerbate general health issues in cancer patients.
• Pregnancy - Contraindicated during pregnancy due to potential harm to the fetus. Effective contraception is essential during treatment.
• Breastfeeding - Not recommended during breastfeeding as the drug may pass into breast milk and could harm the infant.
• Liver - Use with caution in patients with liver impairment. Liver function should be monitored regularly.
• Kidney - Use with caution in patients with kidney impairment. Dose adjustments may be necessary.
• Lung - Monitor for signs of thromboembolic events, including pulmonary embolism, especially in patients with pre-existing risk factors.

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