About
This medication is a selective serotonin receptor agonist, specifically designed for the acute treatment of migraine headaches, with or without aura. It exerts its therapeutic effects by binding to 5-HT1B and 5-HT1D receptors, primarily located on cranial blood vessels and nerve endings. This binding leads to vasoconstriction of dilated intracranial blood vessels, which are thought to contribute to migraine pain. Additionally, it inhibits the release of pro-inflammatory neuropeptides from trigeminal nerve endings, further reducing pain transmission and inflammation. The 5mg dosage is a common starting point for managing moderate to severe migraine attacks. It is not intended for migraine prevention but rather for providing rapid relief once a migraine has started. By addressing both the vascular and neurological components of a migraine, it effectively alleviates headache pain, nausea, photophobia (light sensitivity), and phonophobia (sound sensitivity), allowing patients to resume their daily activities. Proper timing of administration is key for optimal efficacy.
Uses
- Acute treatment of migraine with or without aura
- Relief of moderate to severe migraine pain
- Alleviation of associated symptoms like nausea and light sensitivity
- Off-label use for cluster headaches (for some triptans)
Directions For Use
Take one tablet orally at the first sign of a migraine attack. Do not take more than directed within 24 hours.
Benefits
- Rapid relief of migraine pain
- Reduces associated symptoms (nausea, light/sound sensitivity)
- Effective for moderate to severe migraines
- Improves ability to function during an attack
- Well-tolerated by many patients
- Available in various formulations for convenience
Side Effects
- Chest tightness or pressure
- Neck pain or stiffness
- Tingling or numbness sensation
- Dizziness or drowsiness
- Nausea or dry mouth
- Flushing (redness and warmth)
- Weakness or fatigue
- Jaw pain or discomfort
- Feeling hot or cold
- Serotonin syndrome (rare, with other serotonergic drugs)
- Increased blood pressure
- Palpitations
Safety Measures
- Alcohol - Alcohol can worsen migraine symptoms and increase side effects like dizziness and drowsiness. Limit or avoid during a migraine attack.
- Pregnancy - Use only if clearly needed and benefits outweigh potential risks. Consult your doctor before use.
- Breastfeeding - Small amounts may pass into breast milk. Generally considered safe for occasional use, but consult your physician.
- Liver - Use with caution in patients with hepatic impairment. Dose adjustment may be necessary.
- Kidney - Generally safe for patients with kidney conditions, but caution is advised in severe impairment.
- Lung - Contraindicated in patients with uncontrolled hypertension or ischemic heart disease. Use with caution in patients with severe asthma or COPD due to potential vasoconstrictive effects.
Disclaimer
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| Shop Location | Assam, India |
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