About
Nicardia XL 60mg Tablet, containing Nifedipine extended-release, is a dihydropyridine calcium channel blocker primarily used in the management of hypertension and chronic stable angina. The extended-release (XL) formulation ensures a sustained therapeutic effect, allowing for convenient once-daily dosing. It works by inhibiting the influx of calcium ions into vascular smooth muscle cells and myocardial cells, leading to significant peripheral vasodilation, a reduction in systemic vascular resistance, and a decrease in myocardial oxygen demand. This pharmacological action effectively results in a sustained reduction in blood pressure and provides relief from anginal symptoms. Its prolonged action helps maintain consistent blood pressure control throughout the day, improving patient adherence and overall cardiovascular outcomes.
Uses
- Treatment of essential hypertension.
- Management of chronic stable angina pectoris.
- Raynaud's phenomenon.
- Pulmonary hypertension (off-label).
Directions For Use
Take orally once daily, preferably with food. Swallow the tablet whole; do not crush, chew, or divide.
Benefits
- Effective blood pressure reduction.
- Reduces frequency and severity of angina.
- Once-daily dosing for convenience.
- Sustained therapeutic effect.
- Improves exercise tolerance in angina.
- Well-established safety profile.
Side Effects
- Headache
- Dizziness
- Flushing
- Peripheral edema
- Palpitations
- Fatigue
- Nausea
- Constipation
- Gingival hyperplasia
- Hypotension
- Rash
- Muscle cramps
Safety Measures
- Alcohol - Avoid or limit alcohol consumption as it can enhance the hypotensive effect and cause dizziness.
- Pregnancy - Use with caution; consult a physician. Only if the potential benefit justifies the potential risk to the fetus.
- Breastfeeding - Exercise caution; consult a physician. Nifedipine is excreted in breast milk.
- Liver - Use with caution in severe liver impairment, as metabolism may be significantly affected, requiring dose adjustment.
- Kidney - Generally safe in kidney impairment, but use with caution in severe cases and monitor for adverse effects.
- Lung - Generally safe for patients with lung conditions, but monitor for any exacerbation of symptoms.
Disclaimer
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| Shop Location | Assam, India |

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