OCTUNE 100MG 1AMPULE

About

Octune 100mg, likely referring to Octreotide, is a synthetic analogue of the naturally occurring hormone somatostatin. It mimics the actions of somatostatin by inhibiting the secretion of various hormones, including growth hormone (GH), thyroid-stimulating hormone (TSH), glucagon, insulin, and gastrointestinal peptides like vasoactive intestinal peptide (VIP) and serotonin. This broad inhibitory action makes it valuable in managing conditions characterized by excessive hormone production or secretion. It is particularly effective in controlling symptoms associated with neuroendocrine tumors and acromegaly.

Administered via injection, Octreotide is used to reduce tumor-related symptoms such as severe diarrhea and flushing in patients with carcinoid syndrome, and to manage the watery diarrhea associated with VIPomas. In acromegaly, it helps to normalize GH and IGF-1 levels, thereby alleviating symptoms and reducing tumor size in some cases. Its ability to constrict splanchnic blood vessels also makes it useful in controlling bleeding from esophageal varices.

Uses

• Management of acromegaly.
• Control of symptoms in neuroendocrine tumors (e.g., carcinoid, VIPomas).
• Treatment of acute bleeding from esophageal varices.
• Management of refractory diarrhea in certain conditions.

Directions For Use

Administer via subcutaneous or intravenous injection as directed by a healthcare professional. Dosage and frequency depend on the condition being treated.

Benefits

• Effectively reduces growth hormone levels in acromegaly.
• Controls severe diarrhea and flushing in carcinoid syndrome.
• Manages symptoms of VIPomas.
• Reduces bleeding from esophageal varices.
• Can decrease tumor size in some neuroendocrine tumors.
• Provides symptomatic relief for various hormone-secreting tumors.

Side Effects

• Nausea
• Diarrhea
• Abdominal pain
• Constipation
• Gallstones or biliary sludge
• Injection site reactions (pain, swelling)
• Bradycardia
• Hyperglycemia or hypoglycemia
• Thyroid dysfunction
• Vitamin B12 deficiency
• Fat malabsorption
• Headache

Safety Measures

• Alcohol - No direct interaction, but general caution is advised, especially if underlying liver conditions are present.
• Pregnancy - Use only if clearly needed and the potential benefits outweigh the risks. Consult your doctor.
• Breastfeeding - Excretion into breast milk is unknown. Caution is advised, and a doctor should be consulted.
• Liver - Dose adjustment may be needed in patients with severe hepatic impairment due to altered drug clearance.
• Kidney - Dose adjustment may be needed in patients with renal impairment, particularly in severe cases.
• Lung - No specific direct lung contraindication. However, monitor for any respiratory changes in critically ill patients.

Disclaimer

MedEHub is committed to delivering reliable, expert-reviewd information to help consumers make informed health decisions. However, the content provided on this website is for informational purposes only and is not intended to replace professional medical advice, diagnosis or treatment.

Always consult your doctor for any medical concerns, and discuss your questions about health conditions or medications with a qualified healthcare professional. Do not ignore or delay seeking professional medical advice based on information found on Med E Hub.

Our goal is to complement, not replace, the essential doctor-patient relationship.