About
Olmesafe 20mg Tablet contains Olmesartan Medoxomil, an angiotensin II receptor blocker (ARB). It works by selectively blocking the binding of angiotensin II to the AT1 receptors found in vascular smooth muscle and other tissues. This action prevents the vasoconstrictive and aldosterone-secreting effects of angiotensin II, leading to vasodilation, reduced peripheral vascular resistance, and a decrease in blood pressure. It is primarily used for the treatment of essential hypertension, helping to reduce the risk of cardiovascular events such as stroke and myocardial infarction. Olmesartan is known for its sustained blood pressure lowering effect and is often chosen for its favorable tolerability profile.
The medication helps to relax blood vessels, allowing blood to flow more easily, which in turn lowers blood pressure. Its mechanism of action also contributes to a reduction in cardiac workload and can have beneficial effects on kidney function in certain patient populations, particularly those with hypertension and type 2 diabetes. Regular use as prescribed is crucial for achieving optimal blood pressure control and mitigating long-term cardiovascular risks.
Uses
- Treatment of essential hypertension
- Reduction of cardiovascular risk in hypertensive patients
- Management of high blood pressure
- Prevention of stroke and heart attack in at-risk individuals
Directions For Use
Take this medicine as advised by your doctor, usually once daily. It can be taken with or without food.
Benefits
- Effectively lowers high blood pressure
- Reduces the risk of stroke and heart attack
- Provides sustained blood pressure control
- Generally well-tolerated with a low incidence of cough
- Helps protect the kidneys in certain hypertensive patients
- Convenient once-daily dosing
Side Effects
- Dizziness
- Headache
- Fatigue
- Nausea
- Diarrhea
- Back pain
- Upper respiratory tract infection
- Flu-like symptoms
- Hyperkalemia (high potassium levels)
- Renal dysfunction
- Hypotension (low blood pressure)
- Angioedema (rare, severe allergic reaction)
Safety Measures
- Alcohol - Avoid or limit alcohol consumption as it may increase the hypotensive effects of Olmesartan, leading to dizziness or lightheadedness.
- Pregnancy - Olmesafe 20mg Tablet is contraindicated during pregnancy, especially in the second and third trimesters, due to the risk of fetal injury or death.
- Breastfeeding - It is not recommended during breastfeeding as Olmesartan may pass into breast milk and potentially harm the infant. Consult your doctor.
- Liver - Use with caution in patients with mild to moderate hepatic impairment. Dose adjustment may be necessary. Not recommended in severe hepatic impairment.
- Kidney - Use with caution in patients with renal impairment. Regular monitoring of kidney function and potassium levels is advised, and dose adjustment may be required.
- Lung - Generally considered safe for use in patients with lung conditions, as it does not typically cause respiratory side effects like cough associated with ACE inhibitors.
Disclaimer
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Always consult your doctor for any medical concerns, and discuss your questions about health conditions or medications with a qualified healthcare professional. Do not ignore or delay seeking professional medical advice based on information found on Med E Hub.
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