RABALKEM IT 20MG/ 150MG Capsule

About

RABALKEM IT 20MG/150MG Capsule is a combination medication designed to address gastroesophageal reflux disease (GERD) and associated dyspeptic symptoms. It comprises Rabeprazole, a proton pump inhibitor (PPI), and Itopride, a prokinetic agent. Rabeprazole works by irreversibly blocking the proton pump in the stomach's parietal cells, thereby significantly reducing the production of gastric acid. This action helps to alleviate symptoms like heartburn, acid regurgitation, and promotes the healing of esophageal erosions caused by acid reflux.

Itopride complements this action by enhancing gastrointestinal motility. It acts as a dopamine D2 receptor antagonist and an acetylcholinesterase inhibitor, which collectively increase acetylcholine levels in the gut. This leads to improved gastric emptying and accelerated transit of food through the digestive tract, reducing feelings of fullness, bloating, and nausea often associated with delayed gastric emptying in GERD patients. The synergistic effect of acid suppression and enhanced motility provides comprehensive relief for complex GERD presentations.

Uses

• Treatment of Gastroesophageal Reflux Disease (GERD)
• Relief from heartburn and acid regurgitation
• Management of dyspepsia (indigestion)
• Alleviation of symptoms associated with delayed gastric emptying

Directions For Use

Take this medicine orally as directed by your physician, usually before meals. Swallow the capsule whole with a glass of water; do not chew or crush it.

Benefits

• Effectively reduces stomach acid production
• Provides rapid relief from heartburn and acid reflux
• Enhances gastric emptying and motility
• Alleviates symptoms of indigestion and bloating
• Promotes healing of esophageal damage
• Offers dual-action approach for comprehensive GERD management

Side Effects

• Headache
• Nausea
• Diarrhea
• Abdominal pain
• Flatulence
• Dizziness
• Constipation
• Dry mouth
• Skin rash
• Fatigue
• Insomnia
• Increased prolactin levels

Safety Measures

• Alcohol - Moderate alcohol intake may be acceptable, but excessive consumption can exacerbate gastric irritation and worsen GERD symptoms.
• Pregnancy - Generally not recommended during pregnancy unless clearly indicated and potential benefits outweigh the risks. Consult your doctor.
• Breastfeeding - Components may be excreted into breast milk. Use with caution and only under medical supervision during breastfeeding.
• Liver - Use with caution in patients with severe liver impairment; dose adjustment may be necessary. Regular monitoring is advised.
• Kidney - Generally considered safe in mild to moderate renal impairment. Dose adjustment may be required in severe kidney disease.
• Lung - No specific contraindications related to lung conditions. However, always inform your doctor about all existing health issues.

Disclaimer

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