ROSAVE 10 15

About

Rosuvastatin is a potent HMG-CoA reductase inhibitor, a class of medications commonly known as statins, primarily used to manage dyslipidemia. It works by blocking an enzyme in the liver responsible for cholesterol production, thereby significantly reducing levels of low-density lipoprotein cholesterol (LDL-C), often referred to as 'bad' cholesterol, total cholesterol, and triglycerides. Concurrently, it helps to increase high-density lipoprotein cholesterol (HDL-C), or 'good' cholesterol. This comprehensive lipid-modifying action is crucial in both the primary prevention of cardiovascular disease in individuals at high risk and the secondary prevention of cardiovascular events in those with established disease. By improving the overall lipid profile, Rosuvastatin helps to stabilize atherosclerotic plaques, reduce inflammation, and enhance endothelial function, contributing to a reduced risk of heart attack and stroke. It is typically prescribed as an adjunct to diet and exercise when lifestyle modifications alone are insufficient to achieve target lipid levels, and regular monitoring of lipid profiles and liver function is essential during therapy to ensure efficacy and safety.

Uses

• Hypercholesterolemia
• Mixed dyslipidemia
• Primary prevention of cardiovascular disease
• Secondary prevention of cardiovascular events

Directions For Use

Take one tablet orally once daily, with or without food, as directed by your physician.

Benefits

• Lowers LDL cholesterol
• Reduces triglyceride levels
• Increases beneficial HDL cholesterol
• Decreases risk of heart attack
• Decreases risk of stroke
• Improves overall lipid profile

Side Effects

• Muscle pain (myalgia)
• Headache
• Nausea
• Abdominal pain
• Weakness (asthenia)
• Dizziness
• Constipation
• Diarrhea
• Rash
• Itching
• Proteinuria
• Pancreatitis (rare)

Safety Measures

• Alcohol - Limit alcohol intake as it can increase the risk of liver problems when combined with Rosuvastatin.
• Pregnancy - Contraindicated in pregnancy due to potential fetal harm. Use effective contraception.
• Breastfeeding - Not recommended during breastfeeding as it may pass into breast milk and harm the infant.
• Liver - Use with caution in patients with liver impairment; regular liver function tests are advised. Contraindicated in active liver disease.
• Kidney - Dose adjustment may be necessary in patients with severe renal impairment.
• Lung - Generally safe for use in patients with lung conditions; no specific contraindications.

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