RTU-Doce RTU 20mg Injection

About

RTU-Doce RTU 20mg Injection contains Docetaxel, a potent antineoplastic agent classified within the taxane family of chemotherapy drugs. Its primary mechanism of action involves disrupting the dynamic equilibrium of microtubules, which are critical components of the cellular cytoskeleton and essential for cell division. Docetaxel achieves this by promoting the assembly of tubulin dimers into stable microtubules while simultaneously inhibiting their depolymerization. This leads to the accumulation of non-functional and hyper-stabilized microtubule bundles within the cell, effectively preventing the normal progression of mitosis. Consequently, cells become arrested in the G2/M phase of the cell cycle, ultimately triggering programmed cell death (apoptosis) and inhibiting tumor proliferation. This cytotoxic effect makes Docetaxel a valuable agent in the treatment of various solid tumors, including breast, non-small cell lung, prostate, and gastric cancers.

Uses

• Treatment of breast cancer.
• Treatment of non-small cell lung cancer.
• Treatment of prostate cancer.
• Treatment of gastric adenocarcinoma.

Directions For Use

Administered intravenously by a healthcare professional. Dosage and frequency are determined by the patient's condition and treatment protocol.

Benefits

• Effective against various solid tumors.
• Induces tumor regression.
• Improves progression-free survival.
• Can be used in combination therapies.
• Offers a treatment option for advanced cancers.
• Helps manage metastatic disease.

Side Effects

• Neutropenia (low white blood cell count)
• Anemia
• Thrombocytopenia (low platelet count)
• Nausea and vomiting
• Diarrhea
• Fatigue
• Hair loss (alopecia)
• Peripheral neuropathy
• Fluid retention
• Hypersensitivity reactions
• Nail changes
• Muscle and joint pain

Safety Measures

• Alcohol - Avoid alcohol during treatment as it may exacerbate side effects and liver toxicity.
• Pregnancy - Contraindicated during pregnancy due to significant risk of fetal harm and teratogenicity.
• Breastfeeding - Not recommended during breastfeeding due to potential excretion into breast milk and harm to the infant.
• Liver - Use with extreme caution in patients with liver impairment; dose reduction or discontinuation may be necessary.
• Kidney - Generally safe for use in patients with kidney conditions, but monitoring is advised.
• Lung - Caution in patients with pre-existing lung conditions due to potential for interstitial lung disease.

Disclaimer

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