TAXOCARE 120MG INJ VIAL

About

Taxocare 120MG Injection VIAL contains Docetaxel, an antineoplastic agent belonging to the taxane class of chemotherapy drugs. Docetaxel exerts its cytotoxic effects by promoting the assembly of microtubules from tubulin dimers and inhibiting their depolymerization, leading to the stabilization of microtubules. This action disrupts the normal mitotic process and interphase cellular functions, ultimately inhibiting cell division and inducing apoptosis in rapidly proliferating cancer cells.

It is widely used in the treatment of various solid tumors, including breast cancer, non-small cell lung cancer, prostate cancer, gastric adenocarcinoma, and head and neck cancer. Docetaxel is administered intravenously, often as part of a multi-drug chemotherapy regimen. Due to its potent effects, careful monitoring for adverse reactions, particularly myelosuppression and fluid retention, is essential throughout the treatment course.

Uses

• Breast cancer (adjuvant and metastatic)
• Non-small cell lung cancer
• Prostate cancer (hormone-refractory)
• Gastric adenocarcinoma

Directions For Use

Administered intravenously by a qualified healthcare professional. Dosage and infusion rate are determined by the physician based on the patient's condition.

Benefits

• Effective against various types of cancer
• Can prolong survival in metastatic disease
• Part of established chemotherapy regimens
• Offers treatment option for advanced cancers
• Improves disease-free survival
• Well-established efficacy profile

Side Effects

• Myelosuppression (neutropenia)
• Fluid retention (edema)
• Alopecia (hair loss)
• Nausea and vomiting
• Fatigue and asthenia
• Peripheral neuropathy
• Mucositis
• Skin reactions
• Hypersensitivity reactions
• Nail changes
• Diarrhea
• Anemia

Safety Measures

• Alcohol - Avoid alcohol consumption during Docetaxel treatment due to potential for increased liver strain and exacerbation of gastrointestinal side effects.
• Pregnancy - Docetaxel is contraindicated in pregnancy due to its teratogenic potential; effective contraception is required during and after treatment.
• Breastfeeding - Breastfeeding is contraindicated during Docetaxel therapy and for a period after, as the drug may be excreted in breast milk.
• Liver - Use with caution in patients with hepatic impairment; dose adjustments are necessary, and liver function should be closely monitored.
• Kidney - Use with caution in patients with renal impairment; monitor kidney function, though no specific dose adjustment is typically needed for mild-moderate impairment.
• Lung - Monitor for signs of interstitial lung disease or acute respiratory distress syndrome, which are rare but serious adverse effects.

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