TERBINAFORCE 500M

About

TERBINAFORCE 500M contains Terbinafine at a higher strength, an allylamine antifungal agent specifically designed for more severe or extensive fungal infections. Its mechanism involves the selective inhibition of squalene epoxidase, an enzyme critical for the biosynthesis of ergosterol, a vital component of the fungal cell membrane. This inhibition leads to an intracellular accumulation of squalene, which is toxic to the fungal cell, and a concomitant deficiency of ergosterol. The resulting disruption of the fungal cell membrane's integrity and function ultimately leads to the death of the fungal organism. This higher dose is often prescribed for stubborn or widespread dermatophyte infections affecting the nails, skin, and hair, ensuring potent systemic antifungal action.

Uses

• Treatment of severe onychomycosis (fungal nail infections)
• Management of extensive tinea corporis
• Treatment of widespread tinea cruris
• Alleviation of chronic or severe tinea pedis

Directions For Use

Take one tablet orally once daily, with or without food, for the duration prescribed by your doctor. Adhere strictly to the treatment regimen.

Benefits

• Potent fungicidal action against dermatophytes
• Effective for severe and extensive fungal infections
• Achieves high concentrations in skin, hair, and nails
• Convenient once-daily dosing
• Long-term eradication of fungal pathogens
• Systemic treatment for deep-seated infections

Side Effects

• Headache
• Nausea
• Diarrhea
• Abdominal pain
• Indigestion
• Rash
• Itching
• Taste disturbance (dysgeusia)
• Elevated liver enzymes
• Joint pain
• Muscle pain
• Hair loss (rare)

Safety Measures

• Alcohol - Avoid or limit alcohol consumption as it significantly increases the risk of liver damage when taken with Terbinafine.
• Pregnancy - Generally not recommended during pregnancy due to limited safety data. Use only if the potential benefit outweighs the potential risk to the fetus, after medical consultation.
• Breastfeeding - Terbinafine is excreted into breast milk. Avoid breastfeeding during treatment to prevent infant exposure.
• Liver - Contraindicated in patients with chronic or active liver disease. Baseline and periodic liver function tests are mandatory during treatment.
• Kidney - Use with caution in patients with renal impairment. Dose reduction may be necessary, especially in severe cases (creatinine clearance <50 mL/min).
• Lung - No specific safety concerns related to lung conditions.

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