TOLKEM TAB 10 S

About

TOLKEM, containing Tolperisone, is a centrally acting muscle relaxant used to relieve painful muscle spasms and spasticity. It works by stabilizing neuronal membranes and reducing the excitability of motor neurons, primarily by inhibiting voltage-gated sodium and calcium channels. This action leads to a decrease in the hypertonicity of skeletal muscles without causing significant sedation, which is a common side effect of many other muscle relaxants. Tolperisone is effective in treating muscle spasms associated with various conditions, including musculoskeletal pain, neurological disorders, and post-stroke spasticity. Its unique mechanism of action allows for effective muscle relaxation while preserving mental alertness, making it a preferred choice for patients who need to maintain cognitive function during treatment. It helps to improve mobility and reduce discomfort caused by muscle stiffness.

Uses

• Relief from painful muscle spasms.
• Management of spasticity due to neurological disorders.
• Treatment of musculoskeletal pain.
• Adjunctive therapy for post-stroke spasticity.

Directions For Use

Take orally after meals, as directed by your physician, to enhance absorption and reduce potential gastrointestinal discomfort.

Benefits

• Effectively relieves muscle spasms.
• Reduces muscle stiffness and rigidity.
• Improves overall mobility and flexibility.
• Non-sedating, allowing for maintained alertness.
• Well-tolerated by most patients.
• Effective for various etiologies of muscle hypertonicity.

Side Effects

• Dizziness or drowsiness.
• Nausea and vomiting.
• Abdominal discomfort.
• Headache.
• Muscle weakness.
• Allergic reactions (skin rash, itching).
• Fatigue.
• Dry mouth.
• Hypotension (low blood pressure).
• Anorexia.
• Insomnia.
• Dyspepsia.

Safety Measures

• Alcohol - Avoid or limit alcohol consumption due to potential for increased CNS depression and drowsiness, which can impair coordination.
• Pregnancy - Not recommended unless clearly necessary; limited data available on human pregnancy. Consult a doctor.
• Breastfeeding - Not recommended as it is unknown if Tolperisone is excreted in breast milk. Consult a doctor.
• Liver - Use with caution in patients with liver impairment; dose adjustment may be needed in severe cases.
• Kidney - Use with caution in patients with kidney impairment; dose adjustment may be needed in severe cases.
• Lung - Generally safe, but caution is advised in patients with severe respiratory conditions due to potential for exacerbation.

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