UNICONTIN E 400 10 S

About

UNICONTIN E 400 is a sustained-release formulation of Theophylline, a bronchodilator medication primarily used in the management of respiratory conditions such as asthma and chronic obstructive pulmonary disease (COPD). Theophylline works by relaxing the smooth muscles in the airways of the lungs, leading to bronchodilation and improved airflow. Its mechanism of action involves inhibiting phosphodiesterase enzymes, which increases intracellular cyclic AMP (cAMP) levels, and also by acting as an adenosine receptor antagonist. The sustained-release nature of UNICONTIN E 400 ensures a steady therapeutic concentration of the drug in the bloodstream over an extended period, allowing for less frequent dosing and better symptom control, particularly during the night.

The 400mg strength indicates a specific dosage designed to provide effective bronchodilation while minimizing the risk of side effects. Due to its narrow therapeutic index, careful monitoring of blood levels of Theophylline is often necessary to ensure optimal efficacy and safety. This medication helps to reduce the frequency and severity of asthma attacks and improves breathing in patients with COPD by reducing airway obstruction. It is typically used as a maintenance therapy, rather than for acute relief of bronchospasm, and is often prescribed in conjunction with other respiratory medications to achieve comprehensive disease management.

Uses

• Maintenance treatment of asthma.
• Management of chronic obstructive pulmonary disease (COPD).
• Prevention of nocturnal asthma symptoms.
• Relief of bronchospasm in chronic respiratory conditions.

Directions For Use

Take one tablet once or twice daily, as prescribed by your doctor, swallowed whole with water.

Benefits

• Provides sustained bronchodilation.
• Reduces frequency and severity of asthma attacks.
• Improves breathing in COPD patients.
• Effective for nocturnal symptom control.
• Long-acting formulation for convenient dosing.
• Helps improve lung function over time.

Side Effects

• Nausea
• Vomiting
• Headache
• Insomnia
• Tremors
• Palpitations
• Dizziness
• Restlessness
• Diarrhea
• Abdominal pain
• Irritability
• Seizures (at high doses)

Safety Measures

• Alcohol - Avoid or limit alcohol as it can alter theophylline metabolism and increase side effects.
• Pregnancy - Consult a doctor; use only if clearly needed and benefits outweigh risks.
• Breastfeeding - Consult a doctor; theophylline passes into breast milk and may affect the infant.
• Liver - Use with caution in liver impairment; dose adjustment may be necessary due to altered metabolism.
• Kidney - Use with caution in severe kidney impairment; dose adjustment may be necessary due to altered excretion.
• Lung - Primary indication for lung conditions; monitor for adverse effects.

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