WARF 3 TAB 30 S

About

Warfarin is a widely prescribed oral anticoagulant medication primarily used to prevent the formation and growth of harmful blood clots within the body. It functions as a vitamin K antagonist, specifically by inhibiting the enzyme vitamin K epoxide reductase, which is essential for the activation of several vitamin K-dependent clotting factors, namely factors II, VII, IX, and X, as well as anticoagulant proteins C and S. By interfering with this process, warfarin effectively prolongs the time it takes for blood to clot, thereby significantly reducing the risk of serious thromboembolic events such as strokes, deep vein thrombosis, and pulmonary embolism. Due to its narrow therapeutic window, variable individual response, and numerous potential drug-food interactions, warfarin therapy necessitates meticulous and regular monitoring of the International Normalized Ratio (INR) to ensure optimal therapeutic efficacy while minimizing the significant risk of bleeding complications.

Uses

• Prevention and treatment of deep vein thrombosis (DVT).
• Prevention and treatment of pulmonary embolism (PE).
• Prevention of stroke in patients with atrial fibrillation.
• Prevention of systemic embolism in patients with prosthetic heart valves.

Directions For Use

Take exactly as prescribed by your doctor, usually once daily at the same time. Do not change your dose without consulting your doctor.

Benefits

• Effectively prevents blood clot formation.
• Reduces risk of stroke in atrial fibrillation.
• Prevents recurrent deep vein thrombosis.
• Lowers risk of pulmonary embolism.
• Crucial for patients with mechanical heart valves.
• Well-established and widely used anticoagulant.

Side Effects

• Bleeding (most common and serious)
• Bruising easily
• Nosebleeds
• Gum bleeding
• Blood in urine or stool
• Excessive menstrual bleeding
• Headache
• Dizziness
• Nausea
• Diarrhea
• Skin rash
• Hair loss (rare)

Safety Measures

• Alcohol - Avoid or limit alcohol consumption as it can increase the risk of bleeding or affect warfarin's metabolism.
• Pregnancy - Contraindicated during pregnancy due to teratogenic effects and risk of fetal bleeding; alternative anticoagulants are preferred.
• Breastfeeding - Generally considered safe during breastfeeding as very little passes into breast milk; consult a doctor.
• Liver - Use with caution in patients with liver impairment as it can affect clotting factor synthesis and warfarin metabolism, requiring closer INR monitoring.
• Kidney - Use with caution in patients with severe kidney disease; dose adjustments may be necessary, and closer INR monitoring is advised.
• Lung - No specific contraindications related to primary lung conditions, but caution is needed if lung disease causes bleeding risk.

Disclaimer

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