Xovoltib 40mg Tablet

About

Xovoltib Tablet is an advanced oral tyrosine kinase inhibitor (TKI), representing a cornerstone in targeted cancer therapy for specific malignancies. This medication exerts its anti-cancer effects by precisely blocking the aberrant activity of certain receptor tyrosine kinases (RTKs) or non-receptor tyrosine kinases that are frequently overexpressed or mutated in various cancer cells. These kinases play a critical role in intracellular signaling pathways that drive tumor cell proliferation, survival, angiogenesis, and metastasis. By inhibiting these crucial oncogenic drivers, Xovoltib effectively halts or slows the growth of tumor cells, leading to disease stabilization or regression in eligible patients. Its targeted mechanism allows for a more selective approach compared to traditional chemotherapy, often resulting in a distinct side effect profile. Xovoltib is typically prescribed for patients with specific genetic mutations or biomarkers, underscoring its role in personalized oncology, where treatment decisions are guided by molecular diagnostics to maximize therapeutic benefit and minimize toxicity.

Uses

• Treatment of non-small cell lung cancer (NSCLC) with specific mutations.
• Management of certain advanced solid tumors.
• Treatment of specific gastrointestinal stromal tumors (GIST).
• Used in cases where other therapies have failed or are not tolerated.

Directions For Use

Take Xovoltib Tablet orally, usually once daily, with or without food, as directed by your oncologist. Do not crush, chew, or break the tablet.

Benefits

• Targets specific cancer pathways, leading to effective tumor control.
• Offers a treatment option for advanced or metastatic cancers.
• Can improve progression-free survival in eligible patients.
• Administered orally, providing convenience for patients.
• May have a more favorable side effect profile than conventional chemotherapy.
• Part of a personalized medicine approach in oncology.

Side Effects

• Diarrhea
• Skin rash (acneiform)
• Fatigue
• Nausea and vomiting
• Loss of appetite
• Stomatitis (mouth sores)
• Liver enzyme elevation
• High blood pressure
• Hand-foot syndrome
• Interstitial lung disease (rare but serious)
• Cardiac dysfunction (rare)
• Bleeding events

Safety Measures

• Alcohol - Avoid or limit alcohol consumption as it may exacerbate liver toxicity and other side effects associated with this medication.
• Pregnancy - Xovoltib is contraindicated during pregnancy due to potential harm to the fetus. Effective contraception is required during treatment and for a period afterward.
• Breastfeeding - Breastfeeding is not recommended during treatment with Xovoltib and for a period after the last dose, as it may pass into breast milk and harm the infant.
• Liver - Use with extreme caution in patients with liver impairment. Close monitoring of liver function tests is essential, and dosage adjustments may be required.
• Kidney - Use with caution in patients with severe kidney impairment. Dosage adjustments may be necessary, and renal function should be monitored.
• Lung - Monitor closely for new or worsening respiratory symptoms, as interstitial lung disease is a rare but serious side effect.

Disclaimer

MedEHub is committed to delivering reliable, expert-reviewd information to help consumers make informed health decisions. However, the content provided on this website is for informational purposes only and is not intended to replace professional medical advice, diagnosis or treatment.

Always consult your doctor for any medical concerns, and discuss your questions about health conditions or medications with a qualified healthcare professional. Do not ignore or delay seeking professional medical advice based on information found on Med E Hub.

Our goal is to complement, not replace, the essential doctor-patient relationship.