ZERODOL MR 10'

About

Zerodol MR 10' is a potent combination medication designed to provide comprehensive relief from acute painful musculoskeletal conditions, particularly those involving muscle spasms. It typically comprises an NSAID (Non-Steroidal Anti-Inflammatory Drug) such as aceclofenac, and a muscle relaxant, often thiocolchicoside. Aceclofenac exerts its therapeutic effects by inhibiting the activity of cyclooxygenase (COX) enzymes, thereby reducing the synthesis of prostaglandins, which are key mediators of pain, inflammation, and fever. Concurrently, the muscle relaxant component acts centrally on the spinal cord and brain to alleviate muscle rigidity and spasms, without significantly impairing voluntary muscle movement. This dual mechanism of action makes the formulation highly effective in managing conditions like back pain, sprains, strains, and other inflammatory disorders where both pain and muscle stiffness are prominent symptoms, facilitating improved mobility and comfort for the patient.

Uses

• Relief from acute painful musculoskeletal conditions.
• Treatment of muscle spasms and associated pain.
• Management of low back pain.
• Alleviation of pain and inflammation in conditions like sprains.

Directions For Use

Take one tablet twice daily, or as prescribed by your doctor, preferably after meals to minimize gastrointestinal upset.

Benefits

• Provides effective pain relief.
• Reduces inflammation.
• Relaxes skeletal muscles.
• Improves mobility and flexibility.
• Offers dual action for pain and spasm.
• Fast-acting relief for acute conditions.

Side Effects

• Nausea
• Vomiting
• Diarrhea
• Stomach pain
• Heartburn
• Dizziness
• Drowsiness
• Headache
• Skin rash
• Elevated liver enzymes
• Fluid retention
• Gastrointestinal ulcers (rare but serious)

Safety Measures

• Alcohol - Avoid alcohol as it can increase the risk of stomach bleeding and liver damage, especially with NSAIDs.
• Pregnancy - Generally not recommended, especially in the third trimester, due to potential risks to the fetus; consult a doctor.
• Breastfeeding - Not recommended; components may pass into breast milk and affect the infant.
• Liver - Use with caution in patients with liver impairment; regular monitoring of liver function tests is advised.
• Kidney - Use with caution in patients with kidney disease; NSAIDs can impair renal function.
• Lung - Use with caution in patients with asthma, as NSAIDs can trigger bronchospasm in susceptible individuals.

Disclaimer

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