About
Human Albumin 20% Injection is a sterile solution of albumin, a protein derived from human plasma. Albumin is the most abundant protein in human plasma and plays a critical role in maintaining oncotic pressure, transporting various substances (like hormones, fatty acids, and drugs), and acting as a plasma volume expander. The 20% concentration is hyperoncotic, meaning it draws fluid from the interstitial space into the intravascular compartment, effectively increasing circulating blood volume. It is primarily used in conditions involving hypovolemia, hypoproteinemia, or situations requiring plasma volume expansion, such as shock, burns, acute respiratory distress syndrome, and severe liver disease with ascites. Careful monitoring of fluid balance and electrolyte levels is essential during administration.
Uses
- Treatment of hypovolemic shock.
- Management of severe burns.
- Correction of hypoproteinemia.
- Support in acute respiratory distress syndrome.
Directions For Use
Administer intravenously by a healthcare professional. Dosage and infusion rate are determined by the patient's clinical condition and response.
Benefits
- Effectively expands plasma volume.
- Restores and maintains oncotic pressure.
- Transports vital substances in the blood.
- Supports blood pressure in shock states.
- Aids in fluid mobilization from tissues.
- Reduces edema in certain conditions.
Side Effects
- Allergic reactions (rash, fever, chills)
- Nausea
- Vomiting
- Flushing
- Tachycardia (rapid heart rate)
- Hypotension (low blood pressure)
- Hypertension (high blood pressure)
- Fluid overload
- Pulmonary edema
- Urticaria (hives)
- Headache
- Back pain
Safety Measures
- Alcohol - No direct interaction, but alcohol consumption is generally discouraged in patients requiring albumin due to underlying severe medical conditions.
- Pregnancy - Use only if clearly indicated and the benefits outweigh the potential risks. Consult a doctor.
- Breastfeeding - No specific data on excretion in breast milk. Use with caution and under medical supervision.
- Liver - Often used to manage complications of severe liver disease (e.g., ascites, hepatorenal syndrome). Dosage and monitoring are crucial.
- Kidney - Use with caution in patients with severe renal impairment due to the risk of fluid overload. Monitor kidney function closely.
- Lung - Use with extreme caution in patients with cardiac failure or pulmonary edema due to the risk of fluid overload and exacerbation of lung conditions.
Disclaimer
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Always consult your doctor for any medical concerns, and discuss your questions about health conditions or medications with a qualified healthcare professional. Do not ignore or delay seeking professional medical advice based on information found on Med E Hub.
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