About
Alfuzosin is an alpha-1 adrenergic receptor antagonist specifically designed for the symptomatic treatment of benign prostatic hyperplasia (BPH). This medication exerts its therapeutic effect by selectively blocking alpha-1 receptors located in the smooth muscle of the prostate, bladder neck, and prostatic urethra. The blockade of these receptors leads to relaxation of the smooth muscle tissue, which in turn reduces the dynamic component of bladder outlet obstruction. Consequently, patients experience an improvement in various lower urinary tract symptoms associated with BPH, such as urinary hesitancy, weak stream, nocturia, and a sensation of incomplete bladder emptying. Unlike some other alpha-blockers, alfuzosin is often associated with a lower incidence of orthostatic hypotension, making it a suitable option for many men seeking relief from BPH symptoms.
Uses
- Treatment of benign prostatic hyperplasia (BPH).
- Alleviation of urinary symptoms associated with BPH.
- Improvement of urine flow in men with enlarged prostate.
- Reduction of bladder outlet obstruction.
Directions For Use
Take orally once daily immediately after the same meal each day. Do not crush or chew the tablet.
Benefits
- Effectively relieves BPH symptoms.
- Improves urinary flow rate.
- Reduces frequency of urination.
- Less likely to cause orthostatic hypotension compared to non-selective alpha-blockers.
- Convenient once-daily dosing.
- Enhances quality of life for BPH patients.
Side Effects
- Dizziness
- Headache
- Fatigue
- Nausea
- Abdominal pain
- Orthostatic hypotension (dizziness upon standing)
- Palpitations
- Rhinitis
- Diarrhea
- Ejaculation disorders
- Priapism (rare)
- Intraoperative Floppy Iris Syndrome (IFIS)
Safety Measures
- Alcohol - Avoid or limit alcohol as it can increase the risk of dizziness and orthostatic hypotension.
- Pregnancy - Not applicable for this medication as it is indicated for men.
- Breastfeeding - Not applicable for this medication as it is indicated for men.
- Liver - Contraindicated in severe hepatic impairment; use with caution in mild to moderate impairment.
- Kidney - Use with caution in patients with severe renal impairment; no dosage adjustment typically needed for mild to moderate.
- Lung - Generally safe for use in patients with lung conditions; no specific precautions are usually required.
Disclaimer
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Always consult your doctor for any medical concerns, and discuss your questions about health conditions or medications with a qualified healthcare professional. Do not ignore or delay seeking professional medical advice based on information found on Med E Hub.
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