ALTORAN 80 10 S

About

ALTORAN 80, likely referring to Telmisartan 80mg, is an angiotensin II receptor blocker (ARB) used primarily for the treatment of essential hypertension. It works by selectively blocking the binding of angiotensin II to the AT1 receptor in various tissues, including vascular smooth muscle and the adrenal gland. Angiotensin II is a potent vasoconstrictor and a key component of the renin-angiotensin-aldosterone system (RAAS), which plays a crucial role in regulating blood pressure and fluid balance. By blocking its effects, Telmisartan causes vasodilation, reduces aldosterone secretion, and lowers blood pressure.

Beyond its antihypertensive effects, Telmisartan has demonstrated benefits in reducing cardiovascular morbidity and mortality in patients at high risk, such as those with a history of cardiovascular disease, stroke, or diabetes with end-organ damage. Its long duration of action allows for once-daily dosing, providing sustained blood pressure control. It is generally well-tolerated and is often preferred in patients who develop a cough with ACE inhibitors.

Uses

• Treatment of essential hypertension.
• Reduction of cardiovascular morbidity and mortality.
• Prevention of stroke and myocardial infarction.
• Management of diabetic nephropathy.

Directions For Use

Take one tablet orally once daily, with or without food, as directed by your physician. Swallow the tablet whole with water.

Benefits

• Effective blood pressure lowering.
• Reduces risk of cardiovascular events.
• Long-lasting, once-daily action.
• Well-tolerated, low incidence of cough.
• Provides renal protection in diabetics.
• May improve insulin sensitivity.

Side Effects

• Dizziness.
• Hypotension (especially with first dose).
• Fatigue.
• Back pain.
• Diarrhea.
• Nausea.
• Hyperkalemia (elevated potassium levels).
• Renal dysfunction (especially in susceptible patients).
• Upper respiratory tract infection.
• Cough (less common than ACE inhibitors).
• Muscle cramps.
• Angioedema (rare).

Safety Measures

• Alcohol - Alcohol can increase the hypotensive effect; use with caution and limit intake.
• Pregnancy - Contraindicated during the second and third trimesters due to risk of fetal injury and death.
• Breastfeeding - Not recommended during breastfeeding as it may pass into breast milk and harm the infant.
• Liver - Use with caution in patients with severe hepatic impairment; dose adjustment may be necessary.
• Kidney - Use with caution in patients with renal artery stenosis or severe renal impairment; monitor kidney function closely.
• Lung - Generally safe for patients with lung conditions as it does not directly affect respiratory function.

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