About
Amlokind Beta 25 is a combination medication comprising Amlodipine, a dihydropyridine calcium channel blocker, and Metoprolol, a beta-1 selective adrenergic blocker. Amlodipine exerts its therapeutic effects by relaxing the smooth muscles in blood vessel walls, leading to vasodilation, which effectively lowers blood pressure and enhances the supply of blood and oxygen to the heart muscle. This action is crucial in managing both hypertension and angina.
Metoprolol complements this by selectively blocking beta-1 adrenergic receptors, primarily in the heart. This reduces heart rate, myocardial contractility, and cardiac output, thereby decreasing the heart's workload and oxygen demand. The synergistic action of these two agents provides comprehensive and robust control over essential hypertension and chronic stable angina, significantly improving cardiovascular outcomes and reducing the risk of major adverse cardiac events such as heart attacks and strokes. This fixed-dose combination is particularly beneficial for patients who require more aggressive blood pressure control or who have not achieved target blood pressure with monotherapy.
Uses
- Treatment of essential hypertension.
- Management of chronic stable angina pectoris.
- Prevention of angina attacks.
- Adjunctive therapy in certain cardiovascular conditions.
Directions For Use
Take this medication orally, usually once daily, with or without food, as directed by your physician. Swallow the tablet whole with water.
Benefits
- Effective blood pressure reduction.
- Decreased frequency and severity of angina attacks.
- Improved cardiovascular protection.
- Reduced risk of heart-related complications.
- Enhanced exercise tolerance in angina patients.
- Convenient once-daily dosing for better adherence.
Side Effects
- Dizziness or lightheadedness
- Fatigue or weakness
- Slow heart rate (bradycardia)
- Swelling in ankles or feet (edema)
- Headache
- Nausea or stomach upset
- Cold hands and feet
- Shortness of breath (especially in susceptible individuals)
- Sleep disturbances
- Muscle cramps
- Palpitations
- Diarrhea or constipation
Safety Measures
- Alcohol - Concurrent use of alcohol can enhance the hypotensive effects of this medication, leading to increased dizziness or lightheadedness. It is advisable to limit or avoid alcohol consumption.
- Pregnancy - This medication is generally not recommended during pregnancy, especially in the second and third trimesters, due to potential risks to the fetus. Consult your doctor for alternatives or if benefits outweigh risks.
- Breastfeeding - Both amlodipine and metoprolol are excreted into breast milk. While amounts are generally small, monitor the infant for signs of bradycardia or hypotension. Use with caution and under medical advice.
- Liver - Patients with liver impairment may require dose adjustments as both components are metabolized in the liver. Use with caution and regular monitoring of liver function is recommended.
- Kidney - Dose adjustments may be necessary for patients with severe kidney impairment, particularly for metoprolol. Regular monitoring of kidney function is advised.
- Lung - Metoprolol, a beta-blocker, should be used with extreme caution in patients with bronchial asthma, COPD, or other obstructive lung diseases, as it can exacerbate bronchospasm.
Disclaimer
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Always consult your doctor for any medical concerns, and discuss your questions about health conditions or medications with a qualified healthcare professional. Do not ignore or delay seeking professional medical advice based on information found on Med E Hub.
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| Shop Location | Assam, India |
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