ANFOE 10000 IU 10000

About

ANFOE/ERYPEG (Erythropoiesis-Stimulating Agents) are recombinant forms of human erythropoietin, a glycoprotein hormone naturally produced by the kidneys that plays a crucial role in stimulating red blood cell production. These medications are specifically designed to treat anemia by promoting the proliferation and differentiation of erythroid progenitor cells within the bone marrow, leading to a significant increase in red blood cell count and hemoglobin levels. They are primarily indicated for managing anemia associated with chronic kidney disease, including patients on dialysis, and for anemia in certain cancer patients undergoing chemotherapy. By correcting anemia, these agents help alleviate symptoms such as fatigue and shortness of breath, improving the patient's overall quality of life and reducing the need for blood transfusions.

Uses

• Treatment of anemia associated with chronic kidney disease.
• Anemia in cancer patients receiving chemotherapy.
• Reduction of allogeneic red blood cell transfusions.
• Anemia in certain HIV-infected patients.

Directions For Use

Administer subcutaneously or intravenously as directed by a healthcare professional. Dosage is individualized based on hemoglobin levels and patient response.

Benefits

• Increases red blood cell count and hemoglobin.
• Reduces the need for blood transfusions.
• Improves symptoms of anemia (fatigue, shortness of breath).
• Enhances quality of life for anemic patients.
• Supports oxygen-carrying capacity of blood.
• Effective in various chronic anemic conditions.

Side Effects

• Hypertension (high blood pressure)
• Headache
• Arthralgia (joint pain)
• Nausea
• Vomiting
• Diarrhea
• Injection site pain
• Thrombotic events (e.g., DVT, stroke, MI)
• Seizures
• Allergic reactions
• Pure red cell aplasia (rare)
• Flu-like symptoms

Safety Measures

• Alcohol - No direct interaction, but excessive alcohol can impair liver function and overall health, which may indirectly affect anemia management.
• Pregnancy - Use only if clearly needed and potential benefits outweigh risks; consult a doctor.
• Breastfeeding - It is unknown if ESAs are excreted in human milk; use with caution and consult a healthcare provider.
• Liver - Use with caution in patients with severe liver impairment as the liver plays a role in erythropoietin metabolism.
• Kidney - Often indicated for anemia in chronic kidney disease; monitor blood pressure and hemoglobin closely.
• Lung - No specific contraindications related to lung conditions, but caution is advised in patients with a history of thrombotic events.

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