ARIGABA 100MG

About

Gabapentin is an anticonvulsant medication primarily used to manage partial seizures and various forms of neuropathic pain. Although structurally related to the inhibitory neurotransmitter gamma-aminobutyric acid (GABA), its mechanism of action does not involve direct binding to GABA receptors. Instead, it is believed to exert its therapeutic effects by modulating the activity of voltage-gated calcium channels in the central nervous system, specifically the alpha-2-delta subunit. This modulation leads to a reduction in the release of several excitatory neurotransmitters, which helps to stabilize neuronal activity and alleviate pain signals. Clinically, it is widely prescribed as an adjunctive therapy for partial seizures in adults and children, and for the treatment of postherpetic neuralgia, a persistent nerve pain that can follow shingles. Gabapentin is also utilized off-label for other neuropathic pain conditions and restless legs syndrome. It is generally well-tolerated, but common side effects include dizziness and drowsiness.

Uses

• Adjunctive therapy for partial seizures
• Treatment of postherpetic neuralgia
• Management of restless legs syndrome
• Relief of neuropathic pain (off-label)

Directions For Use

Take this medication with or without food, as directed by your doctor. Swallow capsules whole; do not open or crush them.

Benefits

• Reduces frequency of partial seizures
• Effectively alleviates neuropathic pain
• Improves symptoms of restless legs syndrome
• Generally well-tolerated with a favorable safety profile
• Non-addictive compared to some pain medications
• Can improve sleep quality in pain conditions

Side Effects

• Dizziness
• Drowsiness
• Fatigue
• Ataxia (impaired coordination)
• Nystagmus (involuntary eye movement)
• Tremor
• Peripheral edema (swelling)
• Blurred vision
• Headache
• Nausea
• Weight gain
• Viral infection

Safety Measures

• Alcohol - Avoid alcohol consumption as it significantly increases CNS depression, leading to severe drowsiness, dizziness, and impaired coordination when combined with gabapentin.
• Pregnancy - Gabapentin is a Pregnancy Category C drug. Use only if the potential benefits outweigh the risks. Potential for developmental toxicity has been observed in animal studies.
• Breastfeeding - Gabapentin is excreted into breast milk. Use with caution and monitor the infant for sedation or feeding difficulties. Consult your doctor.
• Liver - Gabapentin is not significantly metabolized by the liver, so dose adjustment is generally not required for liver impairment.
• Kidney - Dose adjustment is required for patients with renal impairment as gabapentin is primarily excreted unchanged by the kidneys. Accumulation can occur.
• Lung - Use with caution in patients with severe respiratory conditions, especially when combined with other CNS depressants, as gabapentin can cause respiratory depression.

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