AVAS 80

About

Atorvastatin is a potent HMG-CoA reductase inhibitor, commonly known as a statin, widely prescribed to lower elevated cholesterol levels. Its mechanism involves blocking a key enzyme in the liver responsible for cholesterol production, thereby significantly reducing the synthesis of low-density lipoprotein (LDL), often referred to as "bad" cholesterol, and triglycerides. Concurrently, it can modestly increase high-density lipoprotein (HDL), or "good" cholesterol. This comprehensive lipid-modifying action plays a crucial role in reducing the risk of major cardiovascular events such as heart attacks and strokes, particularly in individuals diagnosed with hypercholesterolemia or those with established atherosclerotic cardiovascular disease. Atorvastatin is considered a cornerstone therapy for both primary and secondary prevention of cardiovascular disease.

Uses

• Treatment of primary hypercholesterolemia
• Prevention of cardiovascular events
• Reduction of LDL-C and triglycerides
• Management of mixed dyslipidemia

Directions For Use

Take one tablet orally once daily, preferably at the same time each day, with or without food, as prescribed by your doctor.

Benefits

• Significantly lowers LDL cholesterol
• Reduces triglyceride levels
• Decreases risk of heart attack
• Lowers risk of stroke
• Increases HDL cholesterol modestly
• Stabilizes atherosclerotic plaques

Side Effects

• Muscle pain (myalgia)
• Joint pain (arthralgia)
• Headache
• Nausea
• Diarrhea
• Constipation
• Indigestion
• Fatigue
• Insomnia
• Elevated liver enzymes
• Memory impairment (rare)
• Rhabdomyolysis (very rare, serious muscle breakdown)

Safety Measures

• Alcohol - Limit alcohol intake as it can increase the risk of liver problems and muscle side effects.
• Pregnancy - Contraindicated during pregnancy due to potential harm to the fetus. Use effective contraception.
• Breastfeeding - Contraindicated during breastfeeding as it may pass into breast milk and harm the infant.
• Liver - Contraindicated in active liver disease or unexplained persistent elevations of serum transaminases.
• Kidney - Generally safe for use in patients with kidney conditions; no dosage adjustment usually needed.
• Lung - Generally safe for use in patients with lung conditions; no specific precautions related to lung function.

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