About
BACLESTA OD 20MG contains Baclofen in an extended-release (OD - Once Daily) formulation, designed to provide sustained relief from severe muscle spasticity. As a GABA-B receptor agonist, Baclofen acts primarily at the spinal cord level to inhibit both monosynaptic and polysynaptic reflexes. This action leads to hyperpolarization of afferent terminals and a reduction in the release of excitatory neurotransmitters, thereby decreasing the frequency and intensity of muscle spasms, clonus, and associated pain.
The extended-release formulation of BACLESTA OD 20MG ensures a consistent therapeutic effect throughout the day, minimizing fluctuations in symptom control and improving patient adherence. It is particularly beneficial for individuals suffering from chronic spasticity due to various neurological conditions, helping to restore function and enhance quality of life by effectively managing muscle hypertonicity.
Uses
- Long-term management of severe spasticity in multiple sclerosis
- Sustained relief of spasticity following spinal cord injury
- Control of chronic spasticity in cerebral palsy
- Treatment of severe muscle hypertonicity in other neurological disorders
Directions For Use
Take one tablet orally once daily, preferably at the same time each day. Swallow the tablet whole; do not chew, crush, or split.
Benefits
- Provides sustained, once-daily relief from spasticity
- Reduces the frequency and severity of muscle spasms
- Alleviates chronic pain associated with spasticity
- Improves muscle tone and facilitates movement
- Enhances patient compliance with convenient dosing
- Contributes to improved functional independence
Side Effects
- Drowsiness
- Dizziness
- Weakness
- Nausea
- Headache
- Fatigue
- Insomnia
- Confusion
- Hypotension
- Urinary retention
- Constipation
- Withdrawal symptoms if stopped abruptly
Safety Measures
- Alcohol - Avoid alcohol completely, as it can significantly potentiate the central nervous system depressant effects of Baclofen, leading to severe drowsiness and impaired coordination.
- Pregnancy - Consult your doctor. Use only if the potential benefits to the mother clearly outweigh the potential risks to the fetus.
- Breastfeeding - Consult your doctor. Baclofen is excreted in breast milk; caution is advised, and an alternative may be considered.
- Liver - Use with caution in patients with hepatic impairment; regular monitoring of liver function is recommended during treatment.
- Kidney - Significant dose adjustment is necessary in patients with renal impairment due to the primary renal excretion of Baclofen.
- Lung - Use with extreme caution in patients with compromised respiratory function, as Baclofen can cause dose-dependent respiratory depression.
Disclaimer
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Always consult your doctor for any medical concerns, and discuss your questions about health conditions or medications with a qualified healthcare professional. Do not ignore or delay seeking professional medical advice based on information found on Med E Hub.
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| Shop Location | Assam, India |

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